膦甲酸钠对动脉粥样硬化缺血性脑血管病巨细胞病毒激活状态干预及临床疗效对比分析应用  

The clinical curative effect and intervention about activated state of HCMV in ischemic cerebrovascular disease with artherosclerosis patients after using PFA

作　　者：王慧[1] 何俊瑛[1] 高玉林[1] 孔伟丽[1] 

机构地区：[1]河北医科大学第二医院神经内科

出　　处：《脑与神经疾病杂志》2008年第2期137-139,共3页Journal of Brain and Nervous Diseases

基　　金：河北省科技厅重点攻关课题(03276199D)

摘　　要：缺血性脑血管病发病率、致死率、致残率高,已成为危害人类健康的主要疾病。动脉粥样硬化(Artnerosclerosis,As)是缺血性脑血管病的重要病理基础,人巨细胞病毒(Human cytomegalovirus,HCMV)激活感染与动脉粥样硬化关系密切。近年来应用抗疱疹病毒药物,尤其是膦甲酸钠(Foscarnet Sodium,PFA)治疗人巨细胞病毒感染相关性动脉粥样硬化缺血性脑血管病取得了良好效果[1]。但未见PFA对该病治疗中HCMV激活状态的干预和疗效对比分析报告。现本文通过对86例HCMV相关缺血性脑血管病患者的抗病毒治疗的临床观察,为动脉粥样硬化的治疗提供新思路。Ischemic cerebrovascular disease has high incidence,fatality and mutilation rate,it has been became the main disease that hazardous the healthy of humen.Artherosclerosis(AS)is the importantion pathology fundament of ischemic cerebrovascular disease,there is a intimate relationship between activated infection of human cytomegalovirus(HCMV)and AS.Recent years the application of medicines that anti-herper virus,especially Foscarnet Sodium(PFA)obtain good results in the disease that AS associated ischemic cereb...

关 键 词：人巨细胞病毒 膦甲酸钠 

分 类 号：R743.32[医药卫生—神经病学与精神病学]