上消化道间质瘤的内镜及病理学特点分析  

Endoscopic and pathological characteristics of upper gastrointestinal stromal tumors

作　　者：刘华[1] 张海燕[1] 戴素美[1] 王光兰[1] 姚珊珊[1] 刘希双[1] 

机构地区：[1]青岛大学医学院附属医院内镜中心,山东青岛266003

出　　处：《中国内镜杂志》2008年第6期601-603,共3页China Journal of Endoscopy

摘　　要：目的探讨上消化道间质瘤(GIST)的胃镜、超声内镜及病理学特点。方法回顾分析该院2005年7月～2007年7月诊断的43例上消化道GIST的内镜及病理学资料。结果43例GIST中18例经胃镜加病理活检及免疫组织化学法确诊,胃镜下表现为球形或半球形黏膜下隆起,可有脐样溃疡;病理学上GIST细胞以梭形或上皮样细胞为主,成束状排列,免疫组织化学法示CD117,CD34表达阳性率分别为100%及89%,平滑肌肌动蛋白(SMA)及突触素(SYN)无表达;余23例经超声内镜诊断,良性20例,恶性3例,表现为起源于固有肌层的均质或不均质低回声。结论GIST的诊断有赖于胃镜、超声内镜与病理活检、免疫组织化学法相结合。[Objective] To explore the gastroscopy, endoscopic ultrasonography (EUS) and pathological characteristics of upper gastrointestinal stromal tumors (GIST). [Methods] Endoscopic and pathological data of 43 cases with upper GIST from July 2005 to July 2007 were analyzed retrospectively. [Results] 18 cases were diagnosed as GIST by gastroscopy, light microscopy and immunohistochemical features. Endoscopically, GIST showed submucosal protuberant global or half-global lesions, some were presented with bellybutton...

关 键 词：胃肠道间质瘤 内镜检查 超声内镜 病理学 免疫组织化学法 

分 类 号：R735[医药卫生—肿瘤]