双气囊小肠镜在Peutz-Jeghers综合征中的诊治作用  

Role of diagnosis and management of double-balloon enteroscopy for patients with peutz-jeghers syndrome

作　　者：周平[1] 毛高平[1] 曹传平[1] 宁守斌[1] 杨春敏[1] 唐杰[1] 陈英[1] 王建荣[1] 杜斌[1] 

机构地区：[1]空军总医院消化内科,北京100036

出　　处：《中国内镜杂志》2008年第6期575-577,581,共4页China Journal of Endoscopy

基　　金：全军十一五面上课题资助项目;No.:06MA032

摘　　要：目的探讨双气囊小肠镜在诊治Peutz-Jeghers综合征中的应用价值。方法对空军总医院2004年1月～2008年3月经双气囊小肠镜诊治的23例Peutz-Jeghers综合征患者的临床特点和治疗情况进行回顾性分析。小肠息肉可在双气囊小肠镜检查时给予切除,较大无蒂息肉行手术切除。结果22例患者均经双气囊小肠镜检查并结合临床表现特点确诊。21例表现为口唇、四肢末端散在分布的黑/褐色斑,19例以阵发性腹痛为临床突出表现,最早腹痛发病年龄5岁,伴腹胀,血便或无排便、排气。21例患者发现弥漫分布大小不等的胃肠息肉,息肉形态表现为无蒂、亚蒂、长蒂形息肉,呈蘑菇或菜花状,部分息肉表面糜烂,伴溃疡形成。18例患者小肠息肉行双气囊小肠镜下切除,其中17例患者胃、结肠、直肠息肉分别在胃镜、结肠镜下切除,有4例患者因小肠息肉较大而行手术治疗。错构瘤18例,空肠黏液性腺癌1例。结论双气囊小肠镜在Peutz-Jeghers综合征的诊断中具有重要价值,可提高Peutz-Jeghers综合征的治疗效果。[Objective] To evaluate the role of diagnosis and management of double-balloon enteroscopy for patients with Peutz-Jeghers syndrome. [Methods] Retrospective analysis of clinic characteristics and management in 23 patients with PJS treated by double-balloon admitted in airforce general Hospital from January 2004 to March 2008 was conducted. Polyps which diameters were smaller than 0.5 cm were not resected, which diameters were 0.5~3 cm were resected endoscopically, which diameters were larger than 3 cm, espe...

关 键 词：双气囊电子小肠镜 PEUTZ-JEGHERS综合征 治疗 

分 类 号：R596[医药卫生—内科学]