38例原发性骨恶性淋巴瘤的治疗与预后分析  

The Treatment and Analysis of Prognostic Factors of 38 Cases of Primary Malignant Lymphoma of Bone

作　　者：孙永刚[1] 李文[1] 屠重琪[2] 

机构地区：[1]都江堰市第二人民医院外科,四川都江堰611830 [2]四川大学华西医院骨科,四川成都610041

出　　处：《华西医学》2008年第5期993-994,共2页West China Medical Journal

摘　　要：目的:讨论原发性骨恶性淋巴瘤该病的诊断标准,治疗和影响预后的因素。方法:回顾性分析1970年至2005年收治的38例的临床资料,所有患者均无特殊的临床与影像学表现,病变原发于骨骼而无其他组织起源的证据,通过免疫组化检查确诊为原发性骨恶性淋巴瘤。以B型细胞源性为主。结果:手术治疗19例,术后局部放疗9例,全身化疗7例,未行放、化疗3例。单用全身化疗6例,放、化疗结合者12例,未行治疗1例,住院期间死亡1例。出院后随访1~18年,获得随访结果33例,2年内死亡12例,5年与10年生存率分别为41.1%(14/34)和20.1%(7/34)。结论:病理检查,尤其是免疫组化是确诊和分型的重要手段,治疗以放疗结合CMT化疗为主。Objective:To investigate the diagnostic criteria,treatment and analysis prognostic factors of primary non-Hodgkin s lymphomas of the bone(PLB).We report on the experience relative to the diagnosis and treatment of this disease.Methods:Material Review of thirty-eight patients with newly diagnosed PLB were treated from June 1970 to October 2005.The clinical manifestation and radiological appearance of all cases were non specific.The primary lesion located bone and had no evidence of other tissue.All were conf...

关 键 词：原发性骨恶性淋巴瘤 诊断 放疗结合混合用药化疗 影响预后的因素 

分 类 号：R738.1[医药卫生—肿瘤]