以正己醛为载体的乳状液膜分离尿素的研究  

STUDY OF SEPARATION OF UREA THROUGH A LIQUID EMULSION MEMBRANE USING HEXANAL AS A CARRIER

作　　者：李永胜[1] 刘文广[1] 史林启[2] 姚康德[1] 

机构地区：[1]天津大学高分子材料研究所,天津300072 [2]南开大学高分子化学研究所,天津300071

出　　处：《南开大学学报（自然科学版）》2004年第2期121-124,128,共5页Acta Scientiarum Naturalium Universitatis Nankaiensis

基　　金：教育部南开大学-天津大学合作基金资助项目国家自然科学基金资助项目(59503005)

摘　　要：以正己醛为载体、以氧化环糊精为内相捕捉剂制备一种新的乳状液膜,运用其清除分离尿素,旨在研究一种治疗尿毒症或缓解症状的新型疗法.实验发现,当外相尿素溶液浓度为13g／L,载体正己醛含量为5％,内相氧化环糊精浓度为15％,内相pH＝10时,乳状液膜吸附容量为24.7mg／g.内相氧化环糊精的浓度对单位吸附量起决定作用,但是对吸附速率影响不大.内相pH值由于能直接影响内相捕捉剂与尿素结合物的稳定性,所以对单位吸附量有重要影响.此种吸附剂对氨基酸吸附量仅为尿素的1／10,这为其在含大量氨基酸的人体环境中有效清除尿素提供了优良的选择性,避免了其他尿毒症吸附剂普遍存在的吸附选择性低的缺点.The membrane composition and the effect of several important operating parameters such as pH of the liquid emulsion membrane (LEM) and the efficiency of separation, were systematicallly studied by LEM method. The membrane used to extract urea was composed of 5% hexanal as a carrier, 5% Span-80 as the emulsifier and a mixture of 90% paraffin as the solvent. A solution with a concentration of 15% cyclic polyaldehyde was used as the intrnal phase. Results showed that the LEM can selectively adsorb about 25mg urea per gram of the LEM at 37℃ and almost does not adsorb amino acid that is beneficial to human body.

关 键 词：乳状液膜 分离 尿素 氧化环糊精 正己醛 

分 类 号：R692.2[医药卫生—泌尿科学]