经直肠超声检查和前列腺移行区特异抗原密度在前列腺癌穿刺活检中的作用  

Role of Transrectal Ultrasound(TRUS) and Prostate Specific Antigen Density of Transition zone(PSA-TZ)in the Diagnostic Biopsy of Prostate Cancer

作　　者：张艳华[1] 李洁冰[1] 张本平[2] 程文[1] 郑秀兰[1] 郭存丽[1] 刘颖[1] 

机构地区：[1]哈尔滨医科大学附属肿瘤医院超声科,哈尔滨市150081 [2]哈尔滨医科大学附属第二临床医学院

出　　处：《中国超声医学杂志》2008年第S1期76-78,共3页Chinese Journal of Ultrasound in Medicine

基　　金：黑龙江省自然科学基金资助(No.D2007-32)

摘　　要：目的分析经直肠超声(TRUS)和前列腺移行区特异抗原密度(PSA-TZ)在前列腺癌穿刺活检中的作用,探讨个体化经直肠前列腺穿刺方案的可行性。方法依据TRUS结合PSA-TZ选择穿刺点,对64例可疑前列腺癌(PCA)患者,行经直肠前列腺穿刺活检。结果45例PSA-TZ≥0.35ng/ml.cm3,穿刺病理阳性41例,前列腺癌的检出率为91.1%,其中TRUS发现可疑病灶(TRUS+)35例均证实为癌。19例PSA-TZ<0.35ng/ml.cm3,穿刺病理阳性3例,前列腺癌的检出率15.8%,TRUS(+)5例,其中2例证实为癌。此两组患者前列腺癌的检出率差异显著(P<0.01)。结论当PSA-TZ≥0.35ng/ml.cm3,同时TRUS发现可疑病灶,建议行病灶穿刺;当PSA-TZ≥0.35ng/ml.cm3而TRUS阴性,宜行10点穿刺;若PSA-TZ<0.35ng/ml.cm3,TRUS阳性,则行包括病灶在内的6点穿刺。Objective To evaluate the role of TRUS and PSA-TZ in the prostate biopsy and suggest the selection of different biopsy method,To explore the feasibility of individualization of TRUS guided prostate biopsy strategies for prostate cancer detection.Methods According to the TRUS and PSA-TZ biopsy cores were chosen.There were 64 cases who were suspected to suffer from PCA were examined.Results Among 45 patients with PSA-TZ≥0.35 ng/ml.cm3,41 cases were pathologic positive.The detection rate of prostate cancer was...

关 键 词：直肠超声检查 前列腺移行区特异抗原密度 前列腺癌 穿刺活检 

分 类 号：R737.25[医药卫生—肿瘤]