肝动脉、门静脉双介入治疗对肝癌患者微循环状态的影响  

The effect on the microcirculation state of patients with HCC after interventional chemotherapy via hepatic artery and portal vein

作　　者：曹玮[1] 万毅[2] 张洪新[1] 刘毅勇[1] 李小秋[1] 徐哲[1] 李文献[1] 王侃[1] 

机构地区：[1]第四军医大学唐都医院介入科,陕西西安710038 [2]第四军医大学卫生统计学教研室,陕西西安710032

出　　处：《现代肿瘤医学》2008年第11期1958-1959,共2页Journal of Modern Oncology

摘　　要：目的:评价经导管肝动脉、门静脉途径双介入治疗对肝癌患者微循环状态的影响。方法:50例确诊为原发性肝癌患者,经肝动脉化疗栓塞后,再通过脾动脉灌注化疗,用血液分析系统及微循环显微镜检测患者微循环状态;观察患者生存期。结果:双介入治疗后全血低切黏度增加(P<0.05),血浆黏度增加(P<0.05),治疗后田牛氏加权积分增加(P<0.01)。6、12、24个月生存率分别为84.7%、65.3%、43.4%。结论:经导管肝动脉、门静脉途径双介入治疗肝癌可以延长患者生存期,但也能加重微循环障碍。Objective:To evaluate the effect of transcather arterial chemoembolization plus chemotherapy via portal vein [KG(-*9]on the microcirculation state in patients with hepatocellular carcinoma.Methods:Fifty patients with final diagnosis of primary hepatocellular carcinoma received TACE therapy,then were perfused chemotherapy via splenic artery.The microcirculation state was evaluated with blood analysis system and microcirculation microscope.The survival time were recorded.Results:After therapy,the whole blood ...

关 键 词：肝癌 介入治疗 微循环 

分 类 号：R735.7[医药卫生—肿瘤]