胰腺癌早期诊断及外科治疗探讨  

Strategies of early diagnosis and surgical treatment for pancreatic carcinoma

作　　者：武永忠[1,2] 阴继凯[1] 牛瑞霞[3] 侯东祥[2] 赖大年[1] 高德明[1] 何泽生[1] 吴金生[1] 

机构地区：[1]第四军医大学唐都医院普通外科,陕西西安710038 [2]陕西省人民医院肿瘤科,陕西西安710068 [3]西安医学院第二附属医院(陕西辅仁医院)胸外肿瘤科,陕西西安710038

出　　处：《现代肿瘤医学》2008年第11期2039-2041,共3页Journal of Modern Oncology

摘　　要：目的:探讨胰腺癌早期诊断和提高手术疗效的临床措施。方法:回顾性分析我院自1974年-2001年间连续收治的340例胰腺癌的诊断及外科治疗。结果:本组19.1%(65/340)的胰腺癌病例施行了根治性手术,手术死亡率7.7%(5/65),80.9%(275/340)行姑息性手术及探查术。行根治性手术的胰腺癌病例,首发症状多为上腹部隐痛、胀满不适、纳差、乏力和消瘦等非特异性症状,仅16.9%为无痛性黄疸。影像学检查间接征象检出率分别为胆道扩张97.1%,胆囊肿大88.8%,胰管狭窄、中断、移位和增粗93.8%。对有首发症状的高危人群,联用影像学技术检查直接及间接征象,并及早手术探查,有助于胰腺癌早期诊断。Child改良式胰十二指肠切除术后并发症和手术死亡率明显降低。结论:联用影像技术、及早手术探查,早识别,早诊断,早治疗,是提高胰腺癌早期诊断改善疗效的有效措施。根治性手术切除(Child改良术式)为主的综合性治疗仍是治疗本病的主要治疗措施。Objective:To investigate the strategies of the early diagnosis and surgical treatment of pancreatic carci-noma.Methods:Diagnosis and surgical treatment s data of 340 cases with pancreatic carcinoma from 1994 to 2001 were studied retrospectively.Results:19.1% cases (65/340) received radical resections,mortality rate was 7.7%.80.9% cases (275/340) received palliative resections and explorations. 83.1% patients who received radical resec-tion had epigastric pain, abdominal distention, anepithymia , debility, e...

关 键 词：胰腺癌 早期诊断 外科治疗 

分 类 号：R735.9[医药卫生—肿瘤]