肺癌脑转移瘤对地塞米松加甘露醇治疗的反应性与伽玛刀治疗效果的关系  

The relationship between the reactivity to DXT+MT and the efficacy of Gamma knife radiosurgery for brain metastases from lung cancer

作　　者：沈光建[1] 许民辉[1] 邹咏文[1] 耿明英[1] 李飞鹏[1] 

机构地区：[1]中国人民解放军第三军医大学大坪医院野战外科研究所神经外科,重庆400042

出　　处：《中国微侵袭神经外科杂志》2008年第12期540-541,共2页Chinese Journal of Minimally Invasive Neurosurgery

摘　　要：目的探讨肺癌脑转移瘤对合并使用地塞米松(Dexamethasone,DXT)及甘露醇(Mannitol,MT)的反应性与伽玛刀治疗效果的关系。方法回顾性分析37例肺癌脑转移瘤病人的伽玛刀治疗情况。根据对DXT+MT治疗的反应性,将病人分为两组,比较两组病人的伽玛刀治疗效果。结果24例(65%)对DXT+MT治疗反应良好。伽玛刀治疗后,平均随访6.7个月(3～13个月),肿瘤生长得到有效控制32例(87%),其中23例对DXT+MT治疗反应良好。统计分析显示:肿瘤生长控制率在反应良好组中明显较高。结论在肺癌脑转移瘤伽玛刀治疗适应证选择和预后判定中,对DXT+MT治疗的反应性可视为一个粗略标准。Objective To explore the relationship between the reactivity to dexamethasone(DXT) combined with mannitol(MT) and the efficacy of Gamma knife radiosurgery for metastases from lung cancer.Methods Thirty-seven patients harbored metastases from lung cancer treated with Gamma knife were retrospectively reviewed.Based on the reactivity to DXT+MT, these patients were divided into two groups.The Gamma knife radiosurgical outcome was compared between the two groups.Results Of 37 the patients, 24(65%) showed good re...

关 键 词：肿瘤转移 地塞米松 甘露醇 放射外科手术 

分 类 号：R734.2[医药卫生—肿瘤]