^(18)FDG标准化摄取值对非小细胞肺癌三维适形放疗近期疗效的预测作用  

Predictive Significance of ^(18)Fluorodeoxyglucose Standardized Uptake Value in Evaluating the Therapeutic Efficacy of 3-dimenstional Conformal Radiation in Non-Small Cell Lung Cancer

作　　者：裘敬平[1] 党军[1] 王天禄[1] 姚雷[1] 李光[1] 

机构地区：[1]中国医科大学附属第一医院放疗科,沈阳110001

出　　处：《中国医科大学学报》2009年第4期302-304,共3页Journal of China Medical University

摘　　要：目的探讨非小细胞肺癌(NSCLC)患者在三维适形放疗前接受18氟脱氧葡萄糖正电子发射断层扫描(18FDG-PET)及计算得出的标准化摄取值(SUV)对放疗疗效的预测作用。方法41例NSCLC患者三维适形放疗前行18FDG-PET/CT扫描并计算SUV,放疗后3个月评价疾病早期疗效,多因素分析完全缓解、治疗有效的预测因子。结果SUV、状态评分和肿瘤体积影响是完全缓解的预测因素,SUV的OR值为1.717;SUV、状态评分和临床分期影响是治疗有效的预后因素,SUV的OR值为1.123。结论18FDG-PET扫描及计算SUV能够预测NSCLC行三维适形放疗疗效,其敏感性和特异性较高。Objective To evaluate the predictive significance,positron emission tomography(PET)using 18fluorodeoxyglucose(18FDG)and standardized uptake value(SUV)in evaluating the therapeutic efficacy of 3-dimensional conformal radiation in non-small cell lung cancer(NSCLC).Methods Forty-one NSCLC patients underwent PET/CT before 3-dimensional conformal radiation therapy,and SUV was calculated.The therapeutic efficacy of 3-dimensional conformal radiation therapy was evaluated 3 months after radiotherapy according to pa...

关 键 词：标准化摄取值 非小细胞肺癌 三维适形放疗 疗效 

分 类 号：R734.2[医药卫生—肿瘤]