Beneficial Effect of HHI-Ⅰ(活血化瘀注射液Ⅰ号)on Cerebral Microcirculation,Blood-Brain Barrier in Rats and Anti-hypoxic Activity in Mice  

作　　者：赵连根 吴咸中 伍孝先 

机构地区：[1]Tianjin Institute of Acute Abdomen of Integrated Traditional Chinese and Western Medicine

出　　处：《Chinese Journal of Integrative Medicine》2009年第2期128-132,共5页中国结合医学杂志（英文版）

基　　金：Supported by the Science Foundation of Tianjin Health Bureau(No.03021)

摘　　要：Objective:To investigate the effect of HHI-Ⅰ(活血化瘀注射液Ⅰ号) on the cerebral microcirculation,the blood-brain barrier permeability in rats and anti-hypoxic activity in mice.Methods:(1) The blood microcirculation of the brain in rats was investigated by laser Doppler flowmetry with the probes laid on the cerebral pia mater or inserted into the brain parenchyma.(2) The protective action of HHI-Ⅰagainst the brain microcirculation disturbance induced by intravenous injection of high-molecular dextran(10%,9 mL/kg) wa...Objective:To investigate the effect of HHI-Ⅰ(活血化瘀注射液Ⅰ号) on the cerebral microcirculation,the blood-brain barrier permeability in rats and anti-hypoxic activity in mice.Methods:(1) The blood microcirculation of the brain in rats was investigated by laser Doppler flowmetry with the probes laid on the cerebral pia mater or inserted into the brain parenchyma.(2) The protective action of HHI-Ⅰagainst the brain microcirculation disturbance induced by intravenous injection of high-molecular dextran(10%,9 mL/kg) wa...

关 键 词：HHI-Ⅰ cerebral microcirculation blood-brain barrier permeability HYPOXIA 

分 类 号：R285.5[医药卫生—中药学]