响应曲面法优化超声辅助提取金银花总黄酮  

Ultrasound-assisted extraction of total flavonoids from honeysuckle with response surface methodology

作　　者：李晓军[1] 潘宏利[2] 陈花[1] 吴俊林[1] 

机构地区：[1]陕西师范大学物理学与信息技术学院,陕西西安710062 [2]陕西理工学院物理学系,陕西汉中723001

出　　处：《陕西师范大学学报（自然科学版）》2009年第2期81-85,90,共6页Journal of Shaanxi Normal University：Natural Science Edition

基　　金：陕西省自然科学基金资助项目(2005A11)

摘　　要：在单因素试验的基础上,利用响应曲面法对金银花总黄酮超声提取工艺参数进行优化研究.选择超声时间、超声功率以及水料比为自变量,总黄酮提取率为响应值,采用Box-Behnken设计方法,研究各自变量及其交互作用对总黄酮提取率的影响.利用Design Expert软件对数据进行回归分析,得到二次多项式回归方程的预测模型.结果表明,金银花总黄酮超声辅助提取的优化工艺条件为:超声时间21.35 min,超声功率472.24 W,水料比34.62 mL/g.在此工艺条件下金银花总黄酮提取率理论值为9.09%.Based on the single factor test,the optimum conditions for the ultrasonic extraction of total flavonoids from Honeysuckle are investigated by using respone surface methodology.The ultrasonic extraction time,ultrasonic power and the ratio of water to material are studied with Box-Behnken design and their interactive effect on the extraction rate of total flavonoids are also investigated.The predictive model of polynomial quadratic equation is analysed by Design Expert software.The results indicate that the o...

关 键 词：金银花 总黄酮 超声辅助提取 响应曲面法 BOX-BEHNKEN设计 

分 类 号：TQ461[化学工程—制药化工]