速避凝治疗急性脑梗死的临床观察  

Assessment of Fraxiparine Therapy in Acute Cerebral Infarction

作　　者：杨炼红[1] 邢诒刚[1] 黎祥喷[1] 吕瑞妍[1] 

机构地区：[1]广州中山医科大学孙逸仙纪念医院神经科,510120

出　　处：《岭南急诊医学杂志》2001年第2期89-90,共2页Lingnan Journal of Emergency Medicine

摘　　要：目的:观察速避凝对急性脑梗死的疗效与安全性。方法:采用单盲、随机对照方式,将97例急性脑梗死患者分为治疗组51例,对照组46例。其中对照组用传统治疗,治疗组除传统治疗外,加用速避凝治疗10天。观察两组的治疗效果及副作用。结果:治疗组总有效率为88.25％,与对照组的63.03％比较有明显差异(P<0.05);治疗后全血粘度、血浆粘度、红细胞压积、血小板粘附率都有明显改变(P<0.05)。无继发出血等副作用。结论:速避凝治疗急性脑梗死疗效好,副作用少。Objective: To assess the efficacy and safty of Fraxiparine in acute cerebral infarction. Methods: In an open and randomized prospective study, 97 patients with acute cerebral infarction were divided into two groups, which one was treated with Fraxiparine and classical therapy, the other with classical therapy only. Assess the efficacy and safty of the therapy in both group. Results: At the end of the study, the effective rate of 88.25% in Fraxiparine group and 63.03% in classical group were seen, therefore Fraxiparine therapy was more effective than classical therapy in acute cerebral infarction (P<0.05). All of whole blood viscosity, plasma blood viscosity, platelet aggregation in Fraxiparine group were changed(P<0.05). Not any serious side effect in both groups was detected. Conclusions: Fraxiparine was an effective and safe drug in acute cerebral infarction.

关 键 词：急性脑梗死 速避凝 疗效 

分 类 号：R743.33[医药卫生—神经病学与精神病学]