无症状性腔隙性脑梗死与老年收缩期高血压的关系  

Relationship between Silent Lacunar Cerebral Infarction and Isolated Systolic Hypertension in the Elderly

作　　者：屠海玲[1] 周亚[1] 

机构地区：[1]江苏省泗洪县人民医院神经内科,泗洪223900

出　　处：《神经病学与神经康复学杂志》2008年第2期69-70,共2页Journal of Neurology and Neurorehabilitation

摘　　要：目的探讨老年收缩期高血压与无症状性腔隙性脑梗死(SLCI)的发病情况及相关性。方法对125例老年收缩期高血压(ISH 组)和100例对照组(NT 组)临床特点和影像学特点进行分析。结果 ISH 组125例中,有40例腔隙性脑梗死(LCI),占32%,其中 SLCI 24例,占60%。NT 组100例中,LCI 12例,占12%,其中 SLCI 4例,占33.3%。两组患病率有极其显著差异(P<0.01)。SLCI 罹患部位以基底节多见,提示 LCI 的病因主要为高血压,高发生率与收缩期高血压及脉压增大有关。结论(1)LCI 与收缩期高血压的关系密切,SLCI 发病率较高,无症状静止的性质不仅与病灶大小及位于脑静脉区有关,而且与症状常不引起重视也有一定关系;(2)定期体格检查是发现 SLCI 的有效手段,积极干预各种危险因素,早期治疗,有利于改善预后。Objective To study the relationship between silent lacunar cerebral infarction(SLCI)and isolated systolic hepertension(ISH)in the elderly and its correlation.Methods Clinical and neuroimaging features were analysed between the ISH group(125 cases)and the control group(100 cases).Results Of 125 cases in the ISH group,40 had LCI(32%);of 40 cases of LCI,24 cases had SLCI(60%).Of 100 cases in the control group,12 cases had LCI(12%);of 12 cases of LCI,4 cases had SLCI(33.3%).There was a marked difference between the two groups(P<0.01).More SLCI is located in basal ganglion,which suggests that the cause of LCI is mainly due to hypertension.The high occurrence is related to systolic hypertension and pulse pressure increase.Conclusion (1)Lacunar cerebral infarction is closely connected with systolic hypertension.There is a high occurrence of SLCI. The asymptomatic features are connected not only with the focus size and brain venous area,but also with not paying attention to the symptoms.(2)Regular physical check-up is an effective method for discovery of SLCI.Active inter- vention in various risk factors and early treatment are beneficial to improvement of prognosis.

关 键 词：腔隙性脑梗死 无症状性 收缩期高血压 老年人 

分 类 号：R743.33[医药卫生—神经病学与精神病学] R544.1[医药卫生—临床医学]