抑郁障碍患者的Quisi研究  

Study of Quisi in Depression Patients

作　　者：张明岛[1] 陈兴时[1] 楼翡璎[1] 王继军[1] 常峰[1] 

机构地区：[1]上海市精神卫生研究所,上海200030

出　　处：《神经病学与神经康复学杂志》2008年第2期77-79,共3页Journal of Neurology and Neurorehabilitation

基　　金：上海市精神疾病临床医学中心重点课胚资助项目(批准号:K-06-01)

摘　　要：目的探讨 Quisi 在抑郁障碍辅助诊断中的价值及适应证。方法应用德国 Quisi 仪,对24例抑郁障碍患者的睡眠脑电进行全夜测试,并与21名正常受试者进行对照。结果 (1)患者的睡眠潜伏期、醒觉时间、睡眠总时间、觉醒比、睡眠效率、睡眠维持率、快眼动(REM)睡眠潜伏期、第1～4阶段百分比、REM 百分比等指标上,第1轮与第2轮的差异均无显著性(P均>0.05)。(2)与对照组相比,抑郁障碍组 Quisi 改变主要有 REM 睡眠潜伏期缩短等(P<0.05～0.01)。结论在缺乏相关设备的基层医院,Quisi 技术可用于对抑郁障碍的检测。抑郁障碍患者 Quisi 的睡眠脑电特点有待进一步随访。Objective To explore the value and indication of Quisi for diagnosis of depression.Methods The all-night Quisi was recorded from 24 patients with depression and 21 normal controls,by using a Germany Quisi In- strument.Results No statistical differences were found between the first and second night's recordings in sleep pa- rameters(sleep latency,awake time,total sleep time,awake ratio,sleep effect,sleep maintenance,REM latency, percent of S1～S4,percent of REM,etc)(P>0.05).The Quisi of depressive group presented a shorter REM laten- cy than that of normal controls(P<0.05～0.01).Conclusion In hospitals without relevant equipment,Quisi technique may be used for assay of depression disorder.The characteristics of Quisi of depression patient deserve further studying.

关 键 词：抑郁障碍 电生理学 睡眠快速眼运动 

分 类 号：R749.4[医药卫生—神经病学与精神病学]