磁共振快速多序列检查在超早期缺血性卒中溶栓治疗中的应用  

Application of MR Fast Imaging in Thrombolytic Therapy of Ultraacute Cerebral Infarction

作　　者：青科[1] 赵振国[2] 李跃华[2] 隋海晶[2] 沈武钢[1] 赵晓晖[1] 王连文[1] 龚怡[2] 谢秀海[2] 夏卫英[1] 沈健[1] 陆练军[1] 

机构地区：[1]浦东新区人民医院神经内科,上海市201200 [2]浦东新区人民医院影像科,上海市201200

出　　处：《中国卒中杂志》2007年第12期982-985,共4页Chinese Journal of Stroke

摘　　要：目的探讨磁共振(MR)在超早期缺血性卒中溶栓治疗中的应用价值。方法对早期缺血性卒中患者32例行MR快速成像序列检查,并对筛选出的7例超早期缺血性卒中患者行静脉rt-PA静脉溶栓治疗及定期MR复查随访。结果经MR筛选的7例超早期缺血性卒中患者行溶栓治疗后均预后良好,90d改良Rankin评分均≤2分,Barthal指数80～100分,1例溶栓治疗3周后并发无症状性脑出血。结论MR对筛选超早期缺血性卒中溶栓治疗患者和溶栓后复查均有较大应用价值,特别是对时间窗不明确者或发病超过6h者受益更大。Objective To investigate the value of magnetic resonance(MR)in thrombolytic therapy of ultraacute cerebral infarction.Methods Total 32 patients with acute cerebral infarction were examined by MR fast imaging and among them 7 patients with ultraacute cerebral infarction were treated by recombinant human tissue-type plasminogen activator(rt-PA)intravenous injection and followed-up periodically by MR.Results The 7 patients with thrombolytic therapy had better outcome with Modified Rankin Scale of 90d less than 2 and Barthal Index of 80-100 scores.Three weeks after thrombolytic therapy 1 patient had asymptomatic intracranial hemorrhage.Conclusion MR has great value in the screen and follow-up of thrombolytic therapy for the patients,especially for those who have undefined time window or more than 6 hours.

关 键 词：脑梗死 磁共振成像 溶栓治疗 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R445.2[医药卫生—临床医学]