除草剂苯磺隆的合成工艺  

Synthesis of Tribenuronmethyl

作　　者：陆阳[1] 董超宇[2] 陶京朝[3] 

机构地区：[1]信阳农专有机化学教研室,河南信阳464000 [2]开封大学化工系,河南开封475000 [3]郑州大学化学系,河南郑州450001

出　　处：《江苏化工》2007年第2期40-42,共3页Jiangsu Chemical Industry

摘　　要：由邻甲氧羰基苯磺酰胺和氯甲酸甲酯为起始原料,经过酯化、胺解二步反应合成了农药苯磺隆,确定了各步反应的较佳工艺条件。试验表明,反应时间8h;n(邻甲氧羰基苯磺酰胺甲酸甲酯):n(2-甲氨基-4-甲氧基-6-甲基均三嗪)=1∶1.04;甲苯蒸出,补入新鲜甲苯量90.6mL,总收率为81.3%,原药纯度达96%。该工艺具有原料易得,反应步骤少等特点。Tribenuronmethyl was synthesized in a two-step process involving esterification and amination using 2-methoxycarbonyl-sulfamoylbenzoate and methyl chloroformate as starting material. Synthesis conditions were optimized for each step as proven by trials,including a reaction time of 8 h,2-methoxycarbonyl-sulfamoylbenzoatemethylformate:2-dimethamine-4-methoxy-6-methyl-1,3,5-triazine=1∶1.04;Overall yield could reach 81.3% with the product purity of 96%. This process featured the advantages of reactants available and convenient.

关 键 词：邻甲氧羰基苯磺酰胺 合成 苯磺隆 氯甲酸甲酯 缚酸剂 

分 类 号：TQ457.2+3[化学工程—农药化工]