Rhodium catalyzed asymmetric Pauson-Khand reaction using SDP ligands  

作　　者：FAN Baomin1, LI Shen2, XIE Jianhua2, WANG, Lixin2, TU Yongqiang1 & ZHOU Qilin2 1. State Key Laboratory of Applied Organic Chemistry,Lanzhou University,Lanzhou 730000,China 2. State Key Laboratory of Elemento-organic Chemistry,Nankai University,Tianjin 300071, China 

出　　处：《Science China Chemistry》2006年第1期81-87,共7页中国科学（化学英文版）

基　　金：This work was supported by the National Natural Science Foundation of China (Grant Nos. 20132010 and 20272026); the Major State Basic Research Development Program (Grant No. G2000077506); the Ministry of Education of China and the Committee of Science and Technology of Tianjin City for financial support.

摘　　要：The activity and enantiocontrol ability of the chiral catalysts prepared from spiro di-phosphine ligands, SDP, and rhodium precursor were investigated in the asymmetric catalytic Pau-son-Khand reaction. The results showed that SDP ligands were very effective in Rh-catalyzed Pau-son-Khand reaction, and their complexes with rhodium could convert a variety of 1,6-enyne compounds into bicyclopentone derivatives under CO atmosphere in high yields with good enantioselec-tivities. The SbF6- was found to be a suitable counter anion of the catalyst, and 1,2-dichloroethane was the best choice of the solvent for Pauson-Khand reaction.The activity and enantiocontrol ability of the chiral catalysts prepared from spiro di-phosphine ligands, SDP, and rhodium precursor were investigated in the asymmetric catalytic Pau-son-Khand reaction. The results showed that SDP ligands were very effective in Rh-catalyzed Pau-son-Khand reaction, and their complexes with rhodium could convert a variety of 1,6-enyne compounds into bicyclopentone derivatives under CO atmosphere in high yields with good enantioselec-tivities. The SbF6- was found to be a suitable counter anion of the catalyst, and 1,2-dichloroethane was the best choice of the solvent for Pauson-Khand reaction.

关 键 词：Pauson-Khand reaction  ASYMMETRIC catalysis  DIPHOSPHINE ligand  rhodium. 

分 类 号：O643.32[理学—物理化学]