胆汁细菌培养与临床抗生素的应用  

Bile bacterial culture and clinical antibiotic application

作　　者：陈学中[1] 孔刚[1] 杨小清[1] 

机构地区：[1]广东省江门市中心医院,江门529070

出　　处：《中国医药导报》2006年第9期7-9,共3页China Medical Herald

摘　　要：目的通过对360例胆汁细菌培养的结果进行分析,以明确其在指导临床应用抗菌药物中的价值。方法对近5年来胆道手术中获取的胆汁标本进行细菌培养和药敏实验。结果360例胆汁中有190例标本培养出细菌,阳性率为52.5%;共培养出细菌210株,其中革兰氏阴性杆菌132株(占62.8%),革兰氏阳性菌58株(占27.6%),结果显示:大肠埃希氏菌和克雷伯氏菌对常用的氨苄西林、庆大霉素、羧苄西林等耐药率超过90%,铜绿假单胞菌、革兰氏阳性菌出现多重交叉耐药。结论胆道感染病原菌因地域不同而不同,不同菌种对抗生素有不同的耐药性,因此,临床上胆汁细菌培养不应轻易放弃并值得推广,以利合理应用抗生素。Objective Pass to as a result carry on of 360 galls germs development analysis, with explicit it is in guide clinical application of antimicrobial drugs.Methods The bile obtained from biliary tract surgery in resent 5 years was cultured and tested for antibiotics sensitivity. Results There was 190 specimens in 360 galls of result culture a germs, the positivi rate was 52.5%; Culture 210 stubs of a germs totally, among them 132 stubs of the Gram negative bacteria 132( 62.8%)/Gram positive bacteria 58 ( 27.6%).Results Escherichia coli and Klebsiella had better susceptibility to other antibiotics but Ampicillin's, Carbenicillin's, Gentamycin's and Sulfanilamide's resistant strain rate was over 90%. Mucorracemosus,other non-Zymogen,intestiner bacilli and group entercoccus,staphylococcus appeared multi-acrossed medicine resistant.Conclusion The main pathogenic bacteria of bile vary because of region dissimilarity;It was different sensitivities of the antimicrobials to the different bacteria. The bacterial culture could reflectr the actual bacteriological situation, It shouli not be readily abandoned and should be wouth apreading. It is very necessary to select antibiotics correctly according to results of susceptibility test.

关 键 词：胆汁 细菌学 感染 抗感染药 

分 类 号：R[医药卫生]