思利巴联合综合疗法治疗大龄儿童弱视的临床观察  

Primary study of Si Li Ba on treatment for amblyopia in older children

作　　者：曹嵘[1] 

机构地区：[1]河南省商丘市第一人民医院眼科,商丘476100

出　　处：《中国医药导报》2006年第9期9-10,共2页China Medical Herald

摘　　要：目的探讨左旋多巴治疗大龄儿童弱视的疗效.方法对7～14岁82例(135眼)弱视儿童随机分成2组,对照组采用综合治疗,实验组加服左旋多巴.治疗3个月,随访2年,对视力、图形视觉诱发电位(P-VEP)等结果进行分析.结果实验组总有效率76.81%,对照组有效率42.42%,两者之间疗效差异显著(p＜0.05).P-VEP中p100波幅潜伏期缩短,振幅提高.实验组立体视功能的改善较对照组有显著差异.治疗期间无明显副作用.结论左旋多巴能有效提高大龄弱视患儿视力,联合疗法优于综合疗法.Objective To investigate the effect of levodopa treatment for amblyopia in older children.Methods Totally 135 eyes of 82 cases of amblyopic children aged from 7~14 were divided into two groups randomly.The control group had comprehensive treatment.Besides the comprehensive treatment,the experimental group had been treated by levodopa for 3 months .After 3 months of treatment and 2 years of followup,visual acuity,pattern-visual evoked potential(P-VEP) were tested and analyzed.Results The effective rates of amblyopia in experimental group and control group were 76.8%、42.42% respectively.There was a significant difference in the effect rate between erperimental group and control group (P<0.05).Also P-VEP shaved a decrease in latenly of P100 wave and increase of amplitude.The experimental group was better than the contronl group on the improvement of stereoscopic vision.Side effects were minimal during treatment for amblyopia.Conclusion Levodopa was an effective method to improve visual acuity of older childhood amblypoia.United treatment was better than the comprehensive treatment.

关 键 词：弱视 左旋多巴 综合疗法 

分 类 号：R[医药卫生]