1H-MRS和MRI在脑胶质瘤诊断的临床应用  

The clinical application of Proton MR spectroscopy and MRI diagnosis in Brain gliomas

作　　者：娄晓宇[1] 程敬亮[1] 李树新[1] 

机构地区：[1]郑州大学第一附属医院影像科,郑州450052

出　　处：《中国医药导报》2006年第12期19-20,共2页China Medical Herald

摘　　要：目的探讨磁共振成像(MRI)结合氢质子磁共振波谱(1H-MRS)以提高脑胶质瘤的诊断正确性。方法对22例MRI显示胶质瘤表现者配合1H-MRS检查(测NAA、Cho、及Lac波)进行综合诊断。结果1H-MRS显示肿块区NAA下降、Cho升高、Cr略下降或变化不明显和部分出现异常Lac峰,同时可显示肿瘤周边区域的Cho升高等异常。结论MRI影像结合1H-MRS分析能提高脑胶质瘤的诊断正确性,对鉴别诊断、临床选择导航、立体定向活检、制定治疗方案等具有重要的临床应用价值。Objective To evaluate diagnostic accuracy of brain gliomas with MRI and proton MR spectroscopy.Methods 1H-MRS examination (NAA ,Cho , Cr and Lac wave) were carried out for diagnosis in 22 cases with characteristic of gliomas in MRI.Results Decreased NAA and increased Cho, more decrease or more changed Cr was showed in 1H-MRS, some present abnormal Lac peaks and increased Cho in peritumoral area.Conclusion It may be playing an important clinical role not only in evaluating diagnostic accuracy of brain glioma but in differential diagnosis, selecting the clinical therapy direction of guidance operation,stereotactic biopsy and making the treatment plan.

关 键 词：脑胶质瘤 磁共振成像 磁共振波谱 

分 类 号：R[医药卫生]