脑静脉窦血栓形成分析  

The analysis of Cerebral Venous Sinus Thrombosis

作　　者：孙志华[1] 丁俊丽[1] 赵恺[1] 蒋漫红[1] 张前[1] 

机构地区：[1]中国石油天然气集团公司中心医院,河北廊坊065000

出　　处：《中国医药导报》2006年第17期16-18,共3页China Medical Herald

摘　　要：目的探讨和研究脑静脉窦血栓形成(CVST)的临床特点。方法对11例CVST病人的一般情况、起病形式、临床表现、脑脊液特点、影像学特征、治疗及预后等临床资料进行回顾性分析,结合相关文献进行总结。结果多数为急性或亚急性起病,早期表现多为头痛、呕吐,可伴有癫痫发作和各种神经功能缺损的症状体征,脑脊液压力明显升高,白细胞数和蛋白质定量可正常或升高。MRI常规扫描示脑实质内均出现异常信号,MRV示静脉窦闭塞或充盈缺损。治疗以脱水、抗凝、溶栓为主,11例病人中7例基本痊愈,3例好转,1例死亡。结论对于起病较急的高颅压伴或不伴有神经、精神障碍的患者,须高度警惕CVST,应尽早行MRV或DSA检查,对其治疗仍以抗凝、溶栓为主,血管内介入治疗成为新的亮点。Objective To investigate and research the clinical characteristics of cerebral venous sinus thrombosis(CVST).Methods Medical records of 11 CVST patients,including clinical presentations,cerebral spinal fluid (CSF) and findings of neuroimaging,as well as the therapy and prognosis are discussed in comparison with the literatures. Results The onset was most acute or subacute.The first symptom was almost headache and vomit,with epilepsy and focal deficits.As for CSF examination,pressure increased remarkably,with WBC and protein normal or increased.MRI showed the normal flow void of the dural sinus disappeared, instead abnormal high signal intensities were found.The signs of CVST in MRV include loss of vascular flow of the venous sinus.The major treatment involve dehydration,anticoagulation and thrombolysis . There were 7 complete recovery,3 improvement,1 dead. Conclusions The patients with acute onset of intracranial hypertension with or without psychoneurdogical defect should be highly suspected the CVST,thus early combined MRV or DSA are helpful for diagnosis.Anticoagulation and thrombolysis are the main treatment in CVST .Intervention therapy showed new views.

关 键 词：脑静脉窦血栓 诊断 治疗 

分 类 号：R[医药卫生]