米非司酮配伍米索前列醇终止中期妊娠240例分析  

Clinical analysis of 240 cases of mifepristone combined with misoprostol for induced abortion in 12～24 weeks gestation

作　　者：庄秀丽[1] 

机构地区：[1]山东省临沂市人民医院,山东临沂276003

出　　处：《中国医药导报》2006年第33期26-27,共2页China Medical Herald

摘　　要：目的探讨米非司酮配伍米索前列醇用于孕12～24周引产的临床效果。方法选择12～24周妊娠需引产的正常健康孕妇480例随机分为两组,每组240例,观察组口服米非司酮配伍米索前列醇阴道后穹窿放置,对照组依沙吖啶经腹羊膜腔注射,观察引产效果及副作用。结果两组72h内终止妊娠的成功率分别为99.2%和95.0%(P>0.05),观察组完全流产率93.3%,显著高于对照组59.2%(P<0.01),产程较对照组短,出血量和胎盘滞留率显著降低。结论米非司酮配伍米索前列醇用于中期妊娠引产是一种安全、有效、痛苦小、并发症少的方法。Objective To study the clinical effect of mifepristone combined with misoprostol for induced abortion in 12～24 weeks gestation.Methods 480 healthy women of induced abortion in 12～24 weeks,gestation were divided randomly into two groups:240 cases using mifepristone combined with misoprostol were employed in this study.The retrospective methed was used to compare the data with ethacridine group.Results There was a higher percentage of successful induced abortion,shorter duration of abortion,markedly decreased amount of bleeding and placental retention rate among mifepristone combined with misoprostol group.Conclusion Using mifepristone combined with misoprostol terminating 12～24 weeks,gestation is an effective,safe,little pain and complications method.

关 键 词：米非司酮 米索前列醇 中期妊娠 引产 

分 类 号：R[医药卫生]