肺炎衣原体血清感染率与缺血性脑卒中的关系  

Relationship between Chlamydia PneumOnia Serum Infection and Ischemic Stroke

作　　者：李爱东[1] 曾莲意[1] 邓英太[1] 黄宗青[1] 李涛[2] 张国良[2] 

机构地区：[1]广东医学院附属福田医院神经内科,深圳518033 [2]心血管疾病研究所

出　　处：《神经病学与神经康复学杂志》2006年第1期3-4,10,共3页Journal of Neurology and Neurorehabilitation

基　　金：深圳市科研基金(200405201)

摘　　要：目的探讨血肺炎衣原体(CPn)感染与缺血性脑卒中的关系。方法应用微量免疫荧光法(MIF)检测70例缺血性脑卒中患者与70例正常对照者CPn血清特异性IgG、IgM抗体滴度。结果 CPn慢性感染率:病例组为84.3%,对照组为65.7%,两组有显著性差异(P<0.05);CPn急性感染率:病例组为8.6%,对照组为5.7%,两组差异无显著性(P>0.05)。结论 CPn慢性感染可能增加缺血性脑卒中发病的危险性。Objective To explore the relationship between chiamydia pneumonia (CPn) infection and ischemic stroke. Methods Serum specific lgG antibodies and IgM antibodies of chlamydia pneumonia in 70 cases of cerebral infarction and 70 healthy subjects were detected by microimmunofluorescence (MIF). Results The chronic chlamydia pneumonia infection rates were 84.3% and 65.7% respectively in the cerebral infarction group and the control group with significant difference(P<0.01). The acute infection rates were 8.6% (in the cerebral group)and 5.7%(in the control group) respectively, but there was no significant difference between the two groups(P>0.05). Conclusion The chronic chlamydia pneumonia infection may increase the risk of ischemic stroke.

关 键 词：缺血性脑卒中 肺炎衣原体 微量免疫荧光法 

分 类 号：R743.3[医药卫生—神经病学与精神病学]