高同型半胱氨酸血症与进展型卒中的关系  

Relationship between increased plasma homocysteine level and stroke in progression

作　　者：王军[1] 施洪超[1] 王景涛[1] 傅雷[2] 姜建东[1] 

机构地区：[1]南京医科大学附属南京第一医院神经内科,南京江苏210006 [2]南京医科大学附属南京第一医院放免中心,南京江苏210006

出　　处：《神经病学与神经康复学杂志》2006年第4期198-200,共3页Journal of Neurology and Neurorehabilitation

基　　金：南京市卫生局科技发展项目(YKK-0332)

摘　　要：目的研究高同型半胱氨酸(Hcy)血症与进展型卒中(SIP)的关系。方法本研究采用放免荧光法检测法测定47例进展性卒中患者,45例非进展性卒中患者的血浆 Hcy 水平。结果血浆 Hcy 水平在 SIP 组为(25.49±15.73)μmol/L,在非进展性卒中组为(19.78±9.36)μmol/L。SIP 组显著高于非进展性卒中组和对照组。结论 SIP 患者的 Hcy 水平显著高于非进展性卒中患者,其鉴别诊断意义可做进一步研究。Objective To study the relationship between the increased plasma homocysteine(Hcy)level and stroke in progression(SIP).Methods The plasma Hcy,VitB_(12) and folate were determined by radio-immunofluo- rescence in 47 patients with SIP and 45 patients with stable cerebral infarction.Results The plasma Hcy level of the patients with SIP was higher than that of the patients with stable cerebral infarction.The plama folate level of the patients with SIP was lower than that of the patients with stable cerebral infarction.The VitB_(12) was the same(P< 0.05).Conclusion The Hcy level in SIP patients was markedly higher than that in the patients with stable cerebral infarction.The further study of the differential diagnosis should be made.

关 键 词：同型半胱氨酸 脑梗死 进展性卒中 

分 类 号：R743.33[医药卫生—神经病学与精神病学]