国产奈达铂为主化疗方案在放疗增敏中的作用  

Primary research for Radiosensitizing effec in native nedaplantin chemotherapeutic scheme

作　　者：张新忠[1] 吴畏[1] 李黎军[1] 宋宏羽[1] 卜桂兰[1] 林运政[1] 

机构地区：[1]南方医科大学附属深圳宝安医院放疗科,518101

出　　处：《中国医药导报》2005年第11期1-2,共2页China Medical Herald

摘　　要：目的探讨奈达铂(NDP)放疗增敏作用、毒性反应,以及处理措施。方法NDP化疗为主方案(NDP+5Fu)的应用和放射治疗的同步进行。结果近期疗效GR10例,PR5例,骨髓抑制:WBC多为I°,约占60%,Pler I°5例,约占30%,Hb I°8例,约占53.3%。胃肠道反应轻。结论增敏作用肯定,耐受好。WBC影响相对小,而Plet、Hb影响略高,胃肠反应较小,无需水化。Objective To explore nedaplatin (NDP) effect, toxin reaction, treatment method. Methods Treatment with NDP+5Fu and radiotherapy add chemotherapy together. Results Bone marrow: WBC I°, about 60.0%, plet I°, five cases, about 30.0%, Hb I° eight cases, about 53.3%. the reactions of gastrointernational tact is small. Conclusions Radiosensitizing effect is sure, endurance is fine. It has a little relatively influence upon WBC, has a little high influence upon plet、Hb. And the reaction of gastrointernational tract is a light , it is no necessary for hydrate.

关 键 词：奈达铂 放疗增敏 头颈部肿瘤 

分 类 号：R[医药卫生]