744例宫颈上皮内瘤样病变的诊断分析  

Diagnosis of 744 cervical intraepithelial neoplasia

作　　者：张岱[1] 李克敏[1] 廉玉茹[1] 

机构地区：[1]北京大学第一医院妇产科,100034

出　　处：《中国妇产科临床杂志》2003年第1期16-18,共3页Chinese Journal of Clinical Obstetrics and Gynecology

摘　　要：目的　分析宫颈上皮内瘤样病变 (CIN) 10年来发病情况 ,并对其筛查诊断方法进行回顾性分析。方法　回顾总结 1993年 1月～ 2 0 0 2年 12月经阴道镜检查并行宫颈活组织检查的 2 10 7病人 ,检出 74 4例CIN ,分析CIN检出的情况及宫颈涂片细胞学和阴道镜检查对其诊断的意义。结果　CIN的检出率逐年升高 ,宫颈涂片细胞学人工阅片筛查CIN的敏感度为 4 3 9% ,电脑辅助细胞学分析系统 (CCT)筛查CIN的敏感度为72 7% ,阴道镜诊断CIN的敏感度为 88 0 %。 35岁以下未明确诊断意义的不典型鳞状上皮细胞 (ASCUS)患者中CIN检出率明显高于 35岁以上者 ,差异有显著性。结论　CCT对CIN的检出有明显提高 ,优于人工阅片 ,阴道镜指导下宫颈活组织检查是诊断CIN的敏感方法。Objective To analyze screening methods for cervical intraepithelial neoplasia(CIN) and summarize the morbidity of CIN in the last 10 years retrospectively Methods 2107 patients who underwent colposcopy and biopsy from January 1993 to December 2002 were included in the study The morbidity of CIN among this group was reviewed and the sensitivities of computer cytological test(CCT) and artificial examination of Pap smear were compared Results The morbidity of CIN rose year by year The sensitivity of artificial examination of Pap smear is 43 9%,72 7% for CCT and 88 0% for colposcopy In the group atypical squamus cell uncertain sense (ASCUS) patients,CIN morbidity of age below 35 is higher than that of age above 35 Conclusions CCT is more sensitive than artificial examination for discovery of CIN The most sensitive method for CIN diagnosis is biopsy by the aid of colposcope The ASCUS patient under 35-years-old should be paid more attention than those above 35

关 键 词：宫颈上皮内瘤样病变 阴道镜 宫颈涂片细胞学 

分 类 号：R737.33[医药卫生—肿瘤]