回顾性对紫杉醇两种药物在我院临床抗肿瘤治疗应用的前景探讨  

Retrospective analysis of clinical application of home-made and imported paclitaxel in our hospital

作　　者：高远征[1] 陈珊珊[1] 苏畅[1] 付聪[1] 

机构地区：[1]军事医学科学院附属307医院药剂科,北京100039

出　　处：《中国药物应用与监测》2005年第6期14-16,共3页Chinese Journal of Drug Application and Monitoring

摘　　要：目的:对紫杉醇国产与进口药物在肿瘤治疗中的应用情况及药物经济学进行分析和评估。方法:采用回顾性调查方法随机抽查,应用国产和进口紫杉醇的肿瘤患者各15例,进行数据的搜集及整理,分析用量、疗效、副作用及单品种治疗费用。结果:经过探讨初步认定,国产紫杉醇疗效、副作用与进口紫杉醇差异小且价格低,在一定程度上减轻病人负担,国产紫杉醇药品单药治疗费用平均为22785.75元,而进口紫杉醇药品单药治疗费用平均56570.67元。结论:国产与进口紫杉醇在治疗乳腺癌、肺癌、胃癌、卵巢癌的临床疗效均无显著性差异,但品种治疗费用明显降低。Objective:To analyze and evaluate the application conditions and pharmaceutical economics of home-made and imported paclitaxel for the treatment of cancer.Methods:In a retrospective study,15 cancer cases using home-made and another 15 cancer cases using imported paclitaxel were randomly sampled and the data was analyzed with respect to the dosage,therapeutic effect,adverse effect and expense of the drug.Results:There was no significant differences between imported paclitaxel and home-made paclitaxel as to therapeutic effect,adverse effect,while the price of the latter was lower.Conclusion:There was no significant difference between imported paclitaxel and home-made paclitaxel when treating mammary cancer,lung cancer,cancer of stomach and ovarian cancer.The cost of treatment using home-made paclitaxel was lower than imported paclitaxel obviously.

关 键 词：紫杉醇 抗肿瘤 病例分析 

分 类 号：R730.5[医药卫生—肿瘤]