超声引导下经皮乙醇注射治疗甲状腺良性肿瘤  

Percutaneous ethanol injection under ultrasonographic guidance in the treatment of thyroid benign nodules

作　　者：李正江[1] 唐平章[1] 牛丽娟[2] 李洪林[2] 

机构地区：[1]中国医学科学院中国协和医科大学肿瘤医院头颈外科,北京100021 [2]中国医学科学院中国协和医科大学肿瘤医院放射诊断科,北京100021

出　　处：《癌症进展》2004年第4期246-249,共4页Oncology Progress

摘　　要：目的　评价经皮乙醇注射治疗甲状腺良性肿瘤有效性和可行性。方法　 2 0 0 2年 6月至2 0 0 3年 8月 ,14例甲状腺良性肿瘤患者接受超声引导下经皮乙醇注射治疗。超声评价甲状腺结节的大小和性质 ,同时用于确定穿刺针位置。每例平均穿刺 4次 ,平均每次注射乙醇的量为 4ml,平均每例患者注射乙醇的量为 15 8ml,两次穿刺间隔为 1周。结果　 14例患者经穿刺细胞学检查 ,均未发现恶性细胞 ,经乙醇注射治疗后 ,肿瘤部分消失、部分呈不同程度缩小 ,有效率为10 0 %。治愈率为 6 9%左右。超声显示治疗后一周结节体积开始缩小 ,病变内囊性区域相对缩小 ,实性区域相对增多 ,回声增高。其并发症为自限性的。随诊期间未见复发。结论　超声引导下经皮乙醇注射治疗甲状腺良性肿瘤是有效的、安全的 ,可作为外科手术的补充和替代。Objective To evaluate the effectiveness of percutaneous ethanol injection(PEI)under ultrasonographic(US)guidance in the treatment of thyroid benign nodules.Methods Fourteen patients with thyroid benign nodule received PEI treatment under ultrasonographic guidance between June 2002 and Aug 2003.US was used to calculate the size and character of the nodules and to define the position of the puncture during the procedure.The mean was four punctures in each patient.The mean volume of ethanol was 4ml in each puncture.The mean volume of ethanol was 15.8ml in each patient.The interval was one week between two punctures.Results Malignant cells were not found in all of the 14 patients by the cytologic examination.US showed that the nodules shrank one week after the treatment,the cystic region waw comparatively reductive,the solid area was comparatively increase,the echo increased in the solid area.The complications were self-limiting in all patients.No recurrence was observed during the follow-up.Conclusion PEI was an effective safe technique for the treatment of thyroid benign nodules,it was used as the supplement and replace of the surgery.

关 键 词：乙醇 超声 甲状腺肿瘤 治疗 

分 类 号：R736.1[医药卫生—肿瘤]