胃癌患者血清癌胚抗原的检测分析  

Detection and Analysis of Serum Carcinoembryonic Antigen in Patients with Carcinoma of Stomach

作　　者：张慧[1] 杨金玲[1] 赵荣涛[1] 杨晓艳[1] 淡以锐[1] 佟冬[2] 

机构地区：[1]吉林军医学院附属医院检验科,吉林吉林132013 [2]吉林市中心医院,吉林吉林132010

出　　处：《第四军医大学吉林军医学院学报》2001年第2期73-75,共3页

摘　　要：目的　探讨胃癌手术患者血清癌胚抗原 (CEA)、血清铁蛋白 (SF)、β2 微球蛋白 (β2 MG)浓度变化与愈后关系。方法　应用放射免疫分析技术 (RIA)检测胃癌手术患者各时段血清CEA、SF、β2 MG的含量。结果　胃癌患者术前结果高于对照组 ,术后 2 0d结果低于术前水平 ,差异显著 (P <0 .0 5 ) ;术后转移复发患者又高于手术前 ,CEA、SF、β2 MG异常表达率分别为 76 .6 6 %、86 .6 6 %、90 .0 0 % ,明显高于胃癌患者手术前及手术后 (P <0 .0 1)。结论　术前肿瘤标志物浓度在正常水平时 ,术后生存期长 ;若术后转移复发乃至晚期标志物浓度持续上升 。Objective To explore the relationship between the concentration change of CEA,SF,β 2 MG and prognosis in patients with carcinoma of stomach.Methods RIA analysing techniqe was used for detection of CEA,SF,β 2 MG contents in serum of different period.Results The preoperative result in the test group was higher than that in the control group and on the 20th day it was lower than preoperative level with great differences( P <0.05),and also cases with postoperative transfer and relapse were more than pr...

关 键 词：肿瘤标志物 胃癌 放射免疫技术 

分 类 号：R735.2[医药卫生—肿瘤]