线粒体脑肌病八例患者临床与神经影像学分析  

Clinical and neuroradiological features of mitochondrial myopathy and mitochondrial encephamyopathy

作　　者：杭小芳[1] 刘卫国[2] 徐肖[2] 张玲如[2] 

机构地区：[1]姜堰市人民医院神经内科,江苏225500 [2]南京医科大学附属脑科医院神经内科

出　　处：《脑与神经疾病杂志》2010年第4期297-301,共5页Journal of Brain and Nervous Diseases

摘　　要：目的分析线粒体脑肌病患者的临床及神经影像学特点。方法对8例病理确诊线粒体脑肌病患者进行回顾性分析研究。结果本病的主要临床表现为抽搐、运动耐受差、发育迟缓和智能障碍;主要影像学特点为幕上多发脑叶病灶,同时合并其他部位的病变,病灶广泛。结论具有上述临床特征和神经影像学改变者,提示线粒体脑肌病的可能。Objective To analysis the clinical and neuroradiological features of patients with mitochondrial encephalomyopathy for early diagnosis.Methods 8 cases with mitochondrial encephalomyopathy were retrospectively studied.Results The most frequent clinical manifestations were convulsion,fatigue or movement intolerance,growth retardation,and intelligence impairment,while the most predominant neuroimaging findings were brain lobe lesions combined with other parts’ lesions,which were very wide.Conclusion The above complex clinical manifestations and the neuroradiological features are helpful in suggesting mitochondrial encephalomyopathy.

关 键 词：线粒体脑肌病 临床特点 神经影像 

分 类 号：R746[医药卫生—神经病学与精神病学]