Synthesis of cis-(±)-2-Hydroxymethyl-5-(Cytosine-1'-yl)-1,3-Oxathiolane (BCH-189)  

Synthesis of cis-(±)-2-Hydroxymethyl-5-(Cytosine-1'-yl)- 1,3-Oxathiolane (BCH-189)

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作  者:Ji Zhen LI Xue Peng QIU Lian Xun GAO Meng Xian DING 

机构地区:[1]Polymer Chemistry Laboratory,Changchun Institute of Applied Chemistry,Chinese Academy of Sciences,Changchun 130022

出  处:《Chinese Chemical Letters》2001年第6期487-488,共2页中国化学快报(英文版)

摘  要:The target compound BCH-189 was synthesized with high yield via four steps from benzoyloxy acetylaldehyde and p-dithiane-2,5-diol as starting materials. The synthetic route is preferable to what literature reported.The target compound BCH-189 was synthesized with high yield via four steps from benzoyloxy acetylaldehyde and p-dithiane-2,5-diol as starting materials. The synthetic route is preferable to what literature reported.

关 键 词:ANTI-HIV total synthesis BCH-189 

分 类 号:O626[理学—有机化学]

 

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