Humoral and cellular immunogenecity of DNA vaccine based on hepatitis B core gene in rhesus monkeys  

作　　者：Zu Hu Huang1 Hui Zhuang2 Shan Lu3 Ren Hua Guo1 Guo Min Xu2 Jie Cai1 Wan Fu Zhu2 1Department of Infectious Diseases. The First Affiliated Hospital of Nanjing Medical University, Nenjing 210029, Jiangsu Province. China2Faculty of Microbiology, Beijing University, Beijing 100000, China3University of Massachusetts Medical Center 

出　　处：《World Journal of Gastroenterology》2001年第1期102-106,共5页世界胃肠病学杂志（英文版）

基　　金：Project supported by the grant from Science Foundation of Ministry of Health of China, No. 96-1-347.

摘　　要：INTRODUCTIONHepatitis B virus (HBV) is the most commonetiologic agent for infectious liver diseases. It isestimated that there are more than 250 millionchronic HBV carriersin the world today and thereis a significant association among persistentinfection, liver cirrhosis and hepatocellularcarcinoma[1-3].

关 键 词：Vaccines  DNA Animals Antibodies  Viral Antibody Formation Antibody Specificity Cell Division Cells  Cultured Enzyme-Linked Immunosorbent Assay Female Hepatitis B control Hepatitis B Core Antigens Immunity  Cellular Immunoglobulin G Interferon Type II INTERLEUKIN-4 Leukocytes  Mononuclear Macaca mulatta Male Research Support  Non-U.S. Gov't 

分 类 号：R512.62[医药卫生—内科学]