INTERLEUKIN-4

作品数:81被引量:365H指数:10
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相关领域:医药卫生更多>>
相关作者:罗红成宋路瑶罗艳琴侯连兵马云更多>>
相关机构:南昌市第二医院南方医科大学南方医院中国人民解放军第一军医大学上海中医药大学更多>>
相关期刊:《中国中西医结合肾病杂志》《Chinese Medical Sciences Journal》《Open Journal of Obstetrics and Gynecology》《International Journal of Oral Science》更多>>
相关基金:国家自然科学基金广东省医院药学研究基金卫生部科学研究基金辽宁省科技厅资助项目更多>>
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Efficacy of catgut embedding in Baihui(GV20)and Feishu(BL13)and Pishu(BL20)on lung tissue,brain tissue and blood related indexes in rats with allergic rhinitis of lung deficiency type被引量:1
《Journal of Traditional Chinese Medicine》2023年第5期973-982,共10页HUANG Heyin WANG Yichen ZHANG Qinxiu WU Xiaojuan WANG Jiang Li Xiangyu PANG Rui FAN Li CAO Liu TANG Luo 
General Program of the National Natural Science Foundation of China:Regulatory Mechanism of Acupoint Catgut Embedding via Axonal Reflex on Neurogenic Inflammation in Allergic Rhinitis(No.81273985);General Program of the National Natural Science Foundation of China:the Study on the Mechanism of Acupoint Catgut Embedding Therapy for Allergic Rhinitis Based on the Coupling of"Acupoint Nasal Mucosal Sensory Nerve Dendritic Cells"(No.81473523);National Science and Technology Support Program for the Twelfth Five-Year Plan:the Study on Clinical Effect and Operation Standard of Catgut Embedding at Acupoints in Treating Allergic Rhinitis(No.2015BA I04B00)。
OBJECTIVE:To investigate the effects of acupoint catgut embedding for 3 weeks on lung tissue,blood immunoglobulin E(IgE)and interleutin-4(IL-4),brain tissue microglia x-42(OX-42)and toll-like receptor-2(TLR-2)in rats ...
关键词:rhinitis allergic acupoint catgut embedding enzyme-linked immunosorbent assay immunoglobulin E INTERLEUKIN-4 hippocampus toll-like receptor 2 
Mechanism of intervention of medicine combined with mild moxibustion on hypothyroidism rat model
《Journal of Hainan Medical University》2023年第4期46-51,共6页WANG Hong-yang SUN Jia-zi LIU Qing-qing YAN Jing ZHANG Tian-sheng HAO Chong-yao 
Shanxi Provincial Natural Science Foundation Project(202203021211083);College Science and Technology Innovation Project of Shanxi Provincial Education Department(2020L044);Graduate Innovation Program of Shanxi University of Traditional Chinese Medicine(2021CX035)。
Objective:To explore the intervention effect of medicine combined with mild moxibustion on immune factor and Na/I symporter(NIS)in hypothyroidism rat model.Methods:The model was successfully made by intragastric admin...
关键词:HYPOTHYROIDISM INTERLEUKIN-4 INTERLEUKIN-23 Na/I symporter Medicine combined with mild moxibustion 
Interleukin-4 promotes microglial polarization toward a neuroprotective phenotype after retinal ischemia/reperfusion injury被引量:10
《Neural Regeneration Research》2022年第12期2755-2760,共6页Di Chen Cheng Peng Xu-Ming Ding Yue Wu Chang-Juan Zeng Li Xu Wen-Yi Guo 
supported by the National Natural Science Foundation of China, No.81970796(to WYG);Clinical Research Program of the Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, No.JYLJ201905(to WYG);Interdisciplinary Program of Shanghai Jiao Tong University, No.YG2019QNA18(to YW)
Glaucoma results from irreversible loss of retinal ganglion cells(RGCs)through an unclear mechanism.Microglial polarization and neuroinflammation play an important role in retinal degeneration.Our study aimed to explo...
关键词:glaucoma hyper-intraocular pressure in vivo INTERLEUKIN-4 intravitreal injection M2 microglia NEURODEGENERATION neuroprotective effect retinal ganglion cell retinal ischemia-reperfusion 
Transplantation of Mesenchymal Stem Cells Attenuates Acute Liver Failure in Mice via an Interleukin-4-dependent Switch to the M2 Macrophage Anti-inflammatory Phenotype被引量:5
《Journal of Clinical and Translational Hepatology》2022年第4期669-679,共11页Jinglin Wang Haoran Ding Jingchao Zhou Senzhe Xia Xiaolei Shi Haozhen Ren 
This work was funded by the National Natural Science Foundation of China(81872359);Jiangsu Provincial key research and development(BE2020752);the Natural Science Foundation of Jiangsu Province(BK20190114);the Nanjing Medical Science and Technique Development Foundation(QRX17129);Key Project supported by Medical Science and technology development Foundation,Nanjing Department of Health(JQX19002,YKK19070);the Nanjing Science and technology project(201911039);the Fundamental Research Funds for the Central Universities(0214-YG1312037);Project of Modern Hospital Management and Development Institute,Nanjing University and Aid project of Nanjing Drum Tower Hospital Health,Education&Research Foundation(NDYG2020047).
Background and Aims:Transplantation of mesenchymal stem cells(MSCs)derived from bone marrow(BM)is an alternative treatment of acute liver failure(ALF)mainly be-cause of the resulting anti-inflammatory activity.It is n...
关键词:Acute liver failure Mesenchymal stem cells Interleukin 4 MACROPHAGE Wnt signaling pathway 
Interactions of thymic stromal lymphopoietin with interleukin-4 in adaptive immunity during Aspergillus fumigatus keratitis
《International Journal of Ophthalmology(English edition)》2021年第10期1473-1483,共11页Chen Chen Chen-Yang Dai Fang Han Jia-Yin Wu Lin Sun Xin-Yi Wu 
AIM:To investigate the potential interactions of thymic stromal lymphopoietin(TSLP)with interleukin-4(IL-4)in adaptive immunity during fungal keratitis(FK).METHODS:An FK mouse model was induced with Aspergillus fumiga...
关键词:Aspergillus fumigatus KERATITIS thymic stromal lymphopoietin Th2 immune response INTERLEUKIN-4 
Complete withdrawal of glucocorticoids after dupilumab therapy in allergic bronchopulmonary aspergillosis:A case report被引量:2
《World Journal of Clinical Cases》2021年第23期6922-6928,共7页Tadashi Nishimura Tomohito Okano Masahiro Naito Chikashi Tsuji Soichi Iwanaka Yasumasa Sakakura Taro Yasuma Hajime Fujimoto Corina N D'Alessandro-Gabazza Yasuhiro Oomoto Tetsu Kobayashi Esteban C Gabazza Hidenori Ibata 
BACKGROUND Allergic bronchopulmonary aspergillosis(ABPA)is an allergic reaction to Aspergillus species that aggravates bronchial asthma.Previous studies demonstrated the glucocorticoid-sparing effect of dupilumab in p...
关键词:Allergic bronchopulmonary aspergillosis Dupilumab ASTHMA INTERLEUKIN-13 INTERLEUKIN-4 Case report 
Impact of Yupingfengsan Oral Liquid on the Expression of IL-4, IFN-<i>γ</i>and NF-<i>κ</i>B of Allergic Rhinitis Mice
《Yangtze Medicine》2021年第2期125-132,共8页Benyuan Chen Chenggang Mao Yating Wan Lijia Wan 
To observe the impact of Yupingfengsan Oral Liquid on the expression of IL-4 and IFN-γ in AR mice’s serum and expression level of nuclear factor—κB (NF-κB) protein and gene in nasal muc...
关键词:Allergic Rhinitis (AR) Yupingfeng Powder Oral Solution Nuclear Factor-κB (NF-κB) Interleukin-4 (IL-4) γ-Interferon (INF-γ) 
Efficacy of Chinese Medicine Acupoint Application Combined with Montelukast on Children with Perennial Allergic Rhinitis:A Randomized Controlled Trial被引量:5
《Chinese Journal of Integrative Medicine》2020年第11期845-852,共8页LI You-jin ZONG Ming DING Li-feng RUI Xiao-qing MA Bei-yin QIN Li-ping 
Supported by the Medicine Leading Science and Technology Project of Shanghai Municipal Science and Technology Commission(No.15401933800)。
Objective To evaluate the efficacy of Chinese medicine acupoint application(CMAA)combined with Western medicine for perennial allergic rhinitis(PAR)in children.Methods In this prospective,parallel,randomized,placebo-c...
关键词:allergic rhinitis Chinese medicine acupoint application MONTELUKAST interferon gamma/interleukin-4 T helper type 1/T helper type 2 
The Akt/glycogen synthase kinase-3β pathway participates in the neuroprotective effect of interleukin-4 against cerebral ischemia/reperfusion injury被引量:5
《Neural Regeneration Research》2020年第9期1716-1723,共8页Mei Li Wen-Wei Gao Lian Liu Yue Gao Ya-Feng Wang Bo Zhao Xiao-Xing Xiong 
supported by the National Natural Science Foundation of China,Nos.81901994(to BZ)and 81571147(to XXX);the Natural Science Foundation of Hubei Province,China,No.2019CFC847(to WWG);the Fundamental Research Funds for the Central Universities,China,No.2042018kf0149(to ML)
Interleukin-4(IL-4) has a protective effect against cerebral ischemia/reperfusion injury. Animal experiments have shown that IL-4 improves the short-and long-term prognosis of neurological function. The Akt(also calle...
关键词:Akt/glycogen synthase kinase-3βpathway apoptosis autophagy cerebral ischemia/reperfusion injury infarct volume INTERLEUKIN-4 NEUROPROTECTION oxidative stress 
Effect of Black Sea bream extracts on cytokine production inlipopolysaccharide-induced inflammation被引量:1
《BIOCELL》2020年第2期193-199,共7页EUN NA MYOUNGWON CHOI INDAL PARK SUNYOUNG LIM 
Basic Science Research Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Science,ICT and Future Planning(NRF-2017R1A2B4005915)。
We investigated the effect of black sea bream extracts on changes in pro-inflammatory and anti-inflammatory cytokines induced by lipopolysaccharide(LPS)in murine splenocytes.The levels of pro-inflammatory cytokines[in...
关键词:Black Sea BREAM CYTOKINES INTERLEUKIN-4 INTERLEUKIN-6 INTERLEUKIN-17A 
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