This study was supported by the National Natural Science Foundation of China(81403313);the Vertical Development Fund of Beijing University of Chinese Medicine(2019-ZXFZJJ-062).
Objective:To explore the effects of 6-gingerol,asarinin,and deoxyschizandrindthe main components of Zingiber officinale(Willd.)Rosc.(Gan Jiang),Asarum heterotropoides f.var.mandshuricum(Maxim.)(Xi Xin),and Schisandra ...
Background: Rheumatoid arthritis (RA) is a common autoimmune disease in which a combination of risk alleles from different susceptibility genes predisposes the patients to develop clinical symptoms following exposure ...
supported by the National Natural Science Foundation of China(Nos.81974151,31972908,81991500,and 81991502)。
Immunoglobulin G4-related sialadenitis(IgG4-RS)is an immune-mediated fibro-inflammatory disease and the pathogenesis is still not fully understood.The aim of this study was to explore the role and mechanism of interle...
BACKGROUND Allergic bronchopulmonary aspergillosis(ABPA)is an allergic reaction to Aspergillus species that aggravates bronchial asthma.Previous studies demonstrated the glucocorticoid-sparing effect of dupilumab in p...
supported in part by PA Tobacco Settlement Fund(Grant 4100062216,to C.D.,J.Y.J.C);support from the National Institutes of Health Award(AR072731,to J.Y.and EB026035,to X.L.);the National Science Foundation(NSF)Award(CBET-BME1330663,to C.D.)。
Glioblastoma(GBM),the deadliest form of brain cancer,presents long-standing problems due to its localization.Chimeric antigen receptor(CAR)T cell immunotherapy has emerged as a powerful strategy to treat cancer.IL-13-...
Supported by the Grants-in-Aid for Scientific Research,No.[B]5H04503 and No.[C]25460965,No.16K09299 from the Ministry of Education,Culture,Sports,Science,and Technology;the National Center for Global Health and Medicine,No.23-101,No.25-104,No.26-110,No.26-117,and No.27-1406;the MEXT-Supported Program for the Strategic Research Foundation at Private Universities for Waseda University
AIM To clarify the roles of TWEAK and its receptor Fn14 in 5-fluorouracil(5-FU)-induced diarrhea.METHODS Diarrhea was induced in wild-type(WT), Fn14 knockout(KO), and IL-13 receptor(IL-13R)α1 KO BALB/c mice using a s...
AIM:To identify the effects of interleukin(IL)-13 on retinal pigment epithelial(RPE) cells and the IL-13 level in aqueous humor of age-related macular degeneration(AMD) patients.METHODS:IL-13 levels in aqueous...
supported by a grant from the Development of Medical Science and Technology Project of Shandong Province in China,No.2014WS0354;the National Natural Science Foundation of China,No.81272099;the Shandong Medical and Health Science and Technology Development Program Fund for Youth in China,No.2009QZ023;the Natural Science Foundation of Shandong Province in China,No.BS2009YY043
This study aimed to use a mouse model of hypertrophic scarring by mechanical loading on the dorsum of mice to determine whether the nervous system of the skin and inflammation participates in hypertrophic scarring. Re...