INTERLEUKIN-5

作品数:32被引量:78H指数:5
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相关领域:医药卫生更多>>
相关作者:樊华张少杰罗鸿瞿申红叶林松更多>>
相关机构:华中科技大学广西中医药大学广西壮族自治区人民医院华中科技大学同济医学院附属襄樊医院更多>>
相关期刊:《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《World Journal of Gastrointestinal Pharmacology and Therapeutics》《Chinese Medical Journal》更多>>
相关基金:国家自然科学基金“十一五”国家科技支撑计划国家杰出青年科学基金中国博士后科学基金更多>>
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Mepolizumab induced palmoplantar psoriasis:A case report
《World Journal of Clinical Cases》2023年第26期6154-6158,共5页Fabio Artosi Laura Diluvio Martina Vultaggio Elena Campione Luca Bianchi 
BACKGROUND Atopic dermatitis and asthma are two diseases whose pathogenesis is largely attributable to the activation,at least in the initial stages,of T helper(Th)-2 Lymphocytes,the related cytokine axis,and B lympho...
关键词:PSORIASIS INTERLEUKIN-5 MEPOLIZUMAB ASTHMA IMMUNOLOGY Case report 
Neutrophil membrane-camouflaged nanoparticles alleviate inflammation and promote angiogenesis in ischemic myocardial injury被引量:3
《Bioactive Materials》2023年第5期369-382,共14页Dongjian Han Fuhang Wang Zhentao Qiao Bo Wang Yi Zhang Qingjiao Jiang Miaomiao Liu Yuansong Zhuang Quanxu An Yan Bai Jiahong Shangguan Jinying Zhang Gaofeng Liang Deliang Shen 
This work was financially supported by the National Science Foundation of China(Grant Nos.81873493 and 82170271 to DL.S.);Henan Thousand Talents Program(Grant Nos.204200510017to DL.S.).Thanks for the help of the research and innovation team project of the First Affiliated Hospital of Zhengzhou University。
Acute myocardial infarction(AMI)induces a sterile inflammatory response,leading to cardiomyocyte damage and adverse cardiac remodeling.Interleukin-5(IL-5)plays an essential role in developing eosinophils(EOS),which ar...
关键词:Biomimetic nanoparticles INTERLEUKIN-5 EOSINOPHILS ANGIOGENESIS Myocardial infarction 
沉默信号调节因子在慢性鼻-鼻窦炎中的表达及炎性因子对其调节作用被引量:3
《中国耳鼻咽喉头颈外科》2021年第4期257-260,共4页王继国 王虹园 李婷 
目的探讨沉默信号调节因子1(silent information regulator 1,Sirt1)在慢性鼻-鼻窦炎(chronic rhinosinusitis,CRS)中的表达及炎性因子对其调节作用。方法 2017年3月~2019年3月于北京大学滨海医院接受鼻内镜手术治疗的30例CRS患者鼻筛...
关键词:鼻窦炎(Sinusitis) 白细胞介素5(Interleukin-5) 干扰素γ(Interferon-gamma) 沉默信号调节因子1(silent information regulator 1) 
嗜酸粒细胞性慢性鼻窦炎的相关研究被引量:2
《中国耳鼻咽喉头颈外科》2021年第2期129-132,共4页李佳倪 孙立薇 孟粹达 朱冬冬 
国家自然科学基金项目(81870701);吉林省财政厅项目(2018scz042);吉林省卫生科技人才专项项目(2019scz004)。
慢性鼻窦炎(CRS)是耳鼻咽喉科的常见病、多发病,根据细胞的浸润方式可分为嗜酸粒细胞性慢性鼻窦炎(eosinophilic chronic rhinosinusitis,ECRS)和非嗜酸粒细胞性慢性鼻窦炎(non-eosinophilic chronic rhinosinusitis,NECRS)。ECRS较NECR...
关键词:鼻窦炎(Sinusitis) 嗜酸细胞(Eosinophils) 白细胞介素5(Interleukin-5) 白细胞介素10(Interleukin-10) 抗体 单克隆(Antibodies Monoclonal) 
Interleukin-5 promotes ATP-binding cassette transporter A1 expression through miR-211/JAK2/STAT3 pathways in THP-1-dervied macrophages被引量:3
《Acta Biochimica et Biophysica Sinica》2020年第8期832-841,共10页Kong Chen Zhenwang Zhao Gang Wang Jin Zou Xiaohua Yu Dawei Zhang Gaofeng Zeng Chaoke Tang 
The work was supported by the grants from the National Natural Sciences Foundation of China(No.81770461);the Natural Science Foundation of Hunan Province(No.2017JJ2224);Hunan Province Health and Family Planning Scientific Research Project(No.B2019108).
Interleukin-5 (IL-5) is manifested as its involvement in the process of atherosclerosis, but the mechanism is still unknown. In this study, we explored the effect of IL-5 on lipid metabolism and its underlying mechani...
关键词:IL-5 miR-211 JAK2/STAT3 pathway ABCA1 cholesterol efflux 
Synthetic studies toward human interleukin-5被引量:1
《Chinese Chemical Letters》2018年第7期1131-1134,共4页Jinrong Liu Suwei Dong 
financial support from the National Recruitment Program of Global Youth Experts(1000 Plan);Peking University Health Science Center(No. BMU2017QQ008);the State Key Laboratory of Natural and Biomimetic Drugs
Interleukin 5(IL-5) is a human cytokine that regulates eosinophil growth and activation, and it plays essential roles in diseases associated with increased level of eosinophils such as asthma. Many studies have been c...
关键词:Interleukin 5 Eosinophilic disorders ASTHMA Solid phase peptide synthesis Native chemical ligation Mirror-image phage display 
Efficacy and safety of benralizumab in patients with eosinophilic asthma: a meta-analysis of randomized placebo-controlled trials被引量:2
《Frontiers of Medicine》2018年第3期340-349,共10页Ting Liu Faping Wang Geng Wang Hui Mao 
Benralizumab is a monoclonal antibody that targets interleukin-5 receptor α to deplete blood eosinophils and improve the clinical outcomes of allergic asthma. We conducted a meta-analysis to evaluate the safety and e...
关键词:benralizumab anti-interleukin-5 monoclonal antibody eosinophilic asthma META-ANALYSIS 
抗白细胞介素5抗体治疗支气管哮喘疗效与安全性的荟萃分析被引量:4
《中华结核和呼吸杂志》2017年第11期835-844,共10页顾永丽 庞婕 宋甲富 程聪 孙增先 
目的 系统评价抗IL-5抗体治疗支气管哮喘(哮喘)患者的疗效及安全性.方法 根据特定中英文检索词检索PubMed、EMbase、Springer、Ovid、Cochrane Library、ClinicalTrials.gov和CNKI、万方数据库的所有相关临床随机对照研究(RCT),检...
关键词:白细胞介素5 抗体 哮喘 META分析 INTERLEUKIN-5 
Elevated serum interleukin-5 levels in severe chronic obstructive pulmonary disease被引量:1
《Acta Biochimica et Biophysica Sinica》2017年第6期560-563,共4页Jennifer Perret Christine McDonald Vasso Apostolopoulos 
Chronic obstructive pulmonary disease (COPD) is a progressive inflammatory lung disorder which is now ranked third as a leading cause of death [1]. Fixed airflow obstruction that is measured by spirometry following ...
局部变应性鼻炎小鼠模型的建立与研究被引量:8
《中华耳鼻咽喉头颈外科杂志》2016年第7期533-537,共5页陈柏文 瞿申红 李敏 叶林松 张少杰 覃泰杰 樊华 
国家自然科学基金资助项目(81460097)National Nature Science of Foundation of China
目的 建立卵清蛋白(ovalbumin,OVA)诱导的小鼠局部变应性鼻炎(local allergic rhinitis,LAR)和变应性鼻炎(AR)模型,并探讨LAR与AR的区别与联系.方法将30只BALB/c小鼠分为5组,每组6只,分别为Al组(鼻部致敏10 d组)、A1对照组、A2...
关键词:鼻炎 变应性 常年性 局部 白细胞介素5 白细胞介素13 INTERLEUKIN-5 INTERLEUKIN-13 
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