相关期刊:《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《World Journal of Gastrointestinal Pharmacology and Therapeutics》《Chinese Medical Journal》更多>>
BACKGROUND Atopic dermatitis and asthma are two diseases whose pathogenesis is largely attributable to the activation,at least in the initial stages,of T helper(Th)-2 Lymphocytes,the related cytokine axis,and B lympho...
This work was financially supported by the National Science Foundation of China(Grant Nos.81873493 and 82170271 to DL.S.);Henan Thousand Talents Program(Grant Nos.204200510017to DL.S.).Thanks for the help of the research and innovation team project of the First Affiliated Hospital of Zhengzhou University。
Acute myocardial infarction(AMI)induces a sterile inflammatory response,leading to cardiomyocyte damage and adverse cardiac remodeling.Interleukin-5(IL-5)plays an essential role in developing eosinophils(EOS),which ar...
The work was supported by the grants from the National Natural Sciences Foundation of China(No.81770461);the Natural Science Foundation of Hunan Province(No.2017JJ2224);Hunan Province Health and Family Planning Scientific Research Project(No.B2019108).
Interleukin-5 (IL-5) is manifested as its involvement in the process of atherosclerosis, but the mechanism is still unknown. In this study, we explored the effect of IL-5 on lipid metabolism and its underlying mechani...
financial support from the National Recruitment Program of Global Youth Experts(1000 Plan);Peking University Health Science Center(No. BMU2017QQ008);the State Key Laboratory of Natural and Biomimetic Drugs
Interleukin 5(IL-5) is a human cytokine that regulates eosinophil growth and activation, and it plays essential roles in diseases associated with increased level of eosinophils such as asthma. Many studies have been c...
Benralizumab is a monoclonal antibody that targets interleukin-5 receptor α to deplete blood eosinophils and improve the clinical outcomes of allergic asthma. We conducted a meta-analysis to evaluate the safety and e...
Chronic obstructive pulmonary disease (COPD) is a progressive inflammatory lung disorder which is now ranked third as a leading cause of death [1]. Fixed airflow obstruction that is measured by spirometry following ...