Dear Editor,I am Dr.Asako Kodama,affiliated with the Department of Ophthalmology at Eiju General Hospital in Tokyo,Japan.Varicella-zoster virus(VZV)induces two distinct states:the primary infection(varicella)and secon...
Supported by the Beijing Natural Science Foundation (No.7202229).
AIM:To investigate the therapeutic effects of hydrogel dressings on neurotrophic keratitis in rats.METHODS:Male Wistar rats,aged 42–56d,were randomly divided into control,experimental,and treatment groups,each consis...
Supported by the National Natural Science Foundation of China(No.82171019);the Natural Science Foundation of Shandong Province(No.ZR2021MH368);Traditional Chinese Medicine Research Project of Qingdao(No.2020-zyy055);Shandong Qingdao Outstanding Health Professional Development Fund.
AIM:To explore whether CD3ε is involved in the adaptive immunity of Aspergillus fumigatus(A.fumigatus)keratitis in mice and the role of innate and adaptive immunity in it.METHODS:Mice models of A.fumigatus keratitis ...
AIM:To report ocular changes in rabbits after the implementation of three different induction methods to create dry eye(DE)conditions and provides evidence of DErelated disease evolution.METHODS:Experimental methods w...
Supported by the National Natural Science Foundation of China(No.82271052,No.82271058,No.U20A20386);the Taishan Scholar Program(No.tspd20150215,No.tsqn201909188)。
AIM:To evaluate the correlation between Demodex infestation and keratitis,and to assess demodicosis using a simple approach.METHODS:A modified slit lamp illumination(at 40×magnification)was used to observe Demodex ta...
Supported by the Shaanxi Provincial Department of Science and Technology(No.2021SF-331)。
AIM:To characterize changes of corneal nerve morphology and tear indices in patients with neurotrophic keratitis(NK)treated with recombinant human nerve growth factor(rhNGF).METHODS:In a prospective observational stud...
Supported by the Tongji-Rockcheck Life Science and Medicine Research Center(No.202014)。
·AIM:To report a case which keratitis is the first clinical manifestation of COVID-19 that occurred 3 d earlier than the common COVID-19 symptoms.·METHODS:Regular slit lamp examination,corneal scraping test,and ches...
Dear Editor,We are writing to present two case reports of persistent epithelial defect after infectious keratitis successfully treated with sutureless contact lens-type amniotic membrane(AM)transplantation.Infectious ...
AIM: To explore whether nicotinamide adenine dinucleotide phosphate(NADPH) oxidase 2(NOX2) is expressed in fungal keratitis in mice and investigate its role in this disease.METHODS: NOX2 expression was detected in C57...
Bacterial keratitis is an infection of the cornea.This kind of infection can progress quickly and if left untreated,it can eventually cause complete blindness.While Staphylococcus aureus and Pseudomonas aeruginosa are...