Diabetic corneal neuropathy and diabetic retinopathy are ocular complications occurring in the context of diabetes mellitus.Diabetic corneal neuropathy refers to the progressive damage of corneal nerves.Diabetic retin...
AIM:To assess tomographic changes and subclinical edema detection in Fuchs’endothelial corneal dystrophy(FECD)through Scheimpflug tomography in a group of phakic patients contemplating cataract surgery.METHODS:A retr...
Supported by Xi’an Health Committee Research Projects(No.2023yb14);Shaanxi Province Natural Science Basic Research Project(No.2024JC-YBMS-623);Shaanxi Province Science and Technology Plan Project(No.2024SFYBXM-331).
AIM:To assess the corneal high-order aberration(HOA)and its correlation with corneal morphological parameters in patients with bilateral keratoconus(KCN)and unilateral Vogt’s striae.METHODS:A total of 168 eyes of 84 ...
Supported by National Natural Science Foundation of China(No.31571294).
AIM:To investigate the role of transmembrane protein 206(TMEM206)in corneal edema in mice by knockout the TMEM206 gene using CRISPR/Cas9 editing technology.METHODS:TMEM206-knockout mice were generated using the CRISPR...
AIM:To evaluate the clinical outcomes after subsequent implantation of a new intrastromal corneal ring segment(ICRS)model followed by an additional short-arc ICRS implant in keratoconus patients.METHODS:This retrospec...
Background: This case report presents a case of bilateral Thiel-Behnke corneal dystrophy in Denmark. Thiel-Behnke is an autosomal dominant inherited epithelial-stromal TGFBI dystrophy causing visual impairment. Method...
Supported by the National Natural Science Foundation of China (No.81900907,No.81870639);Taishan Scholar Program (No.20231255).
AIM:To describe the surgical procedure of fusiform penetrating keratoplasty(FPK)using multiple trephines of different sizes for treating patients with severe infectious keratitis.METHODS:Fourteen eyes underwent FPK,an...
supported by National Natural Science Foundation of China(No.82070932);the Zhejiang Provincial Natural Science Foundation of China(No.LY19H120002);the internal funding of Wenzhou Medical University(No.KYYW202020,China);The Project of Wenzhou Medical University Affiliated Eye Hospital(No.YNZD2201901,China);the integration project of State Key Laboratory of Ophthalmology,Optometry and Vision Science(No.J02-20190202,China).
Dexamethasone(DEX)is used to treat ocular surface diseases.However,regulating DEX duration in tears while preventing its absorption into the anterior chamber is critical for balancing its therapy effects and the side ...
In his beautiful book,Consilience:The Unity of Knowledge,the eminent biologist Edward O Wilson,advocates the need for integration and reconciliation across the sciences.He defines consilience as“literally a‘jumping ...