A surgical alternative of fusiform penetrating keratoplasty for the management of severe infectious keratitis  

作　　者：Xiao-Lin Qi Li-Chao Wang Miao-Lin Wang Hua Gao 

机构地区：[1]Eye Hospital of Shandong First Medical University,State Key Laboratory Cultivation Base,Shandong Provincial Key Laboratory of Ophthalmology,Shandong Eye Institute,Shandong First Medical University&Shandong Academy of Medical Sciences,Jinan 250021,Shandong Province,China

出　　处：《International Journal of Ophthalmology(English edition)》2024年第8期1431-1436,共6页国际眼科杂志（英文版）

基　　金：Supported by the National Natural Science Foundation of China (No.81900907,No.81870639);Taishan Scholar Program (No.20231255).

摘　　要：AIM:To describe the surgical procedure of fusiform penetrating keratoplasty(FPK)using multiple trephines of different sizes for treating patients with severe infectious keratitis.METHODS:Fourteen eyes underwent FPK,and 15 eyes received conventional penetrating keratoplasty(PK)were included in the study.The best-corrected visual acuity(BCVA),refractive outcomes,endothelial cell density,and postoperative complications were recorded.RESULTS:The FPK group was followed for an average of 15.3±2.1mo,whereas the PK group was followed for 16.1±1.9mo.The corneal ulcers were elliptical-shaped in all 14 eyes in the FPK group.The mean BCVA(logMAR,0.26±0.13)showed no statistically significant differences from that in the PK group(logMAR,0.21±0.12,P>0.05)at 1y after surgery.But the mean curvature,mean astigmatism,and mean spherical equivalent in the FPK group were lower than those in the PK group(P<0.05).Peripheral anterior synechia was observed in one patient in the FPK group,whereas 6 patients in the PK group.Suture loosening and neovascularization were observed in 4 and 5 eyes in the PK group,respectively.No graft immune rejection or elevation of intraocular pressure was observed in the two groups.CONCLUSION:For patients with elliptical-shaped corneas or corneal ulcers,FPK can avoid disrupting of corneal limbus,reduce the risk of postoperative complications,and can result in satisfactory visual quality.

关 键 词：fusiform penetrating keratoplasty multiple trephines infectious keratitis CORNEA 

分 类 号：R772.21[医药卫生—眼科]