AIM:To assess tomographic changes and subclinical edema detection in Fuchs’endothelial corneal dystrophy(FECD)through Scheimpflug tomography in a group of phakic patients contemplating cataract surgery.METHODS:A retr...
The endothelium modulates vascular homeostasis owing to a variety of vasoconstrictors and vasodilators.Endothelial dysfunction(ED),characterized by impaired vasodilation,inflammation,and thrombosis,triggers future car...
Context and Justification: The sigmoido-jugular junction connects two structures of different compositions and has a complex organization. The sinusoidal portion of its endothelium contains muscle cells in adults. Is ...
Objective:The possible enhancing effect of anlotinib on programmed death receptor ligand(PD-L1)antibody and the efficacy-predicting power of PD-L1 in micro-conduit endothelium,including lymphatic endothelial cells(LEC...
supported by the Russian Science Foundation Grant No.22-15-00120.
Red blood cells(RBCs)are the most abundant human blood cells.RBC aggregation and deformation strongly determine blood viscosity which impacts hemorheology and microcirculation.In turn,RBC properties depend on di®erent...
supported by the National Natural Science Foundation of China(82272236);the Plan on Enhancing scientific research in GMU(YCZ)and the Key Emergency Medical Disciplines and Specialties Program of Guangzhou(0F05001)(2021-2023).
BACKGROUND:A pathophysiological feature of septic organ failure is endothelial dysfunction in sepsis(EDS).The physiological and pathological mechanism of sepsis is considered to be vascular leakage caused by endotheli...
supported by the National Natural Science Foundation of China (81972034,92068104 and 82002262 to R.X.);the National Key R&D Program of China (2020YFA0112900 to R.X.);Project of Xiamen Cell Therapy Research Center (3502Z20214001 to R.X.);supported by a the NIH grant of US (R01AR075585,R01HD115274,R01CA282815 to M.B.G.);Career Award for Medical Scientists from the Burroughs Wellcome Fund;a Pershing Square Sohn Cancer Research Alliance and the Maximizing Innovation in Neuroscience Discovery (MIND)Prize;supported by a Jump Start Research Career Development Award from Weill Cornell Medicine;a Study Abroad Scholarships from the Mogam Science Scholarship Foundation。
Osteogenesis imperfecta(OI)is a disorder of low bone mass and increased fracture risk due to a range of genetic variants that prominently include mutations in genes encoding typeⅠcollagen.While it is well known that ...
supported,in whole or in part,by NIH grants HL134934 and HL158909 to YS;Augusta University intramural grant IGPCT00023 to YS;by the Department of Veterans Affairs BX005350 to YS.
Endothelial cells(ECs)form a semi-permeable barrier between the interior space of blood vessels and the un-derlying tissues.Pulmonary endothelial barrier integrity is maintained through coordinated cellular processes ...
Endothelial function plays a pivotal role in cardiovascular health,and dysfunction in this context diminishes vasorelaxation concomitant with endothelial activity.The nitric oxide-cyclic guanosine monophosphate pathwa...
supported by National Natural Science Foundation of China (Grant No.52373151).
The advent of antiproliferative drug-eluting vascular stents can dramatically reduce in-stent restenosis via inhibiting the hyperproliferation of vascular smooth muscle cells.However,the antiproliferative drugs also r...