Type 2 diabetes mellitus(T2DM)emerges as a global health crisis and is characterized by hyperglycemia,insulin resistance,and oxidative stress.Conventional treatments for T2DM often have limitations,thus prompting inte...
Background Diet plays a crucial role in insulin resistance and diabetes,with high-fat and high-carbohydrate diets being major contributors.However,the type of fat consumed is critical,as different fatty acids impact i...
Medical Ethics Committee of the Nanxishan Hospital of Guangxi Zhuang Autonomous Region(Approval No.NXSYY-2024-209).
BACKGROUND The preservation of isletβ-cell function in elderly patients with type 2 diabetes mellitus(T2DM)is a top priority for diabetic control.AIM To assess the preservation of isletβ-cell function among elderly ...
Correction to:Acta Pharmacologica Sinica https://doi.org/10.1038/s41401-022-00878-7,published online 25 February 2022 The authors are very sorry for an inadvertent mistake in the CTRL group of Fig.2h:the image of the ...
supported by the National Natural Science Foundation of China(32122069 and 31972191);the Beijing Outstanding Young Scientist Program(BJJWZYJH01201910011025);funded by National Institutes of Health Grants DK111958 and AG062344 to R.J.L.
The present study reports the structural characteristics of 3 polysaccharide fractions(SPS-F1,SPS-F2 and SPS-F3)isolated and purified from squash.SPS-F1(molecular weight(Mw)=12.30 kDa)and SPS-F2(Mw=19.40 kDa)were like...
Background:Coccinia grandis(L.)Voigt,commonly known as Ivy gourd,is a plant of the Cucurbitaceae family that has been used in traditional medicinal systems for centuries.Its most common traditional use is managing dia...
financially supported by the Biotechnology Industrial Research Assistance Council(BIRAC),New Delhi,India(Project Grant No.BT/GUAR-GUM0005/01/19).
In this study,guar gum(GG)was chemically modified to its carboxymethyl derivative,which was then esterified with octenyl succinic anhydride(OSA)using a nucleophilic catalyst 4-dimethylaminopyridine(DMAP)to render the ...
Endothelial function plays a pivotal role in cardiovascular health,and dysfunction in this context diminishes vasorelaxation concomitant with endothelial activity.The nitric oxide-cyclic guanosine monophosphate pathwa...
Objective: The objective of this study was to assess adherence to antidiabetic therapy in type II diabetic patients and factors associated with Lomé. Method: This was a descriptive observational study conducted among...
Supported by Central Talent Training Project for the Reform and Development of Local Colleges and Universities(2020GSP16);Guidance Project of Key R&D Plan in Heilongjiang Province(GZ20220039);Innovation and Entrepreneurship Training Program for College Students in Heilongjiang Province(202310223173).
In this paper,the pharmacological effects and molecular mechanisms of sarsasapogenin,such as anti-oxidant,anti-inflammatory and anti-diabetic effects,are reviewed in order to provide a theoretical basis for the subseq...