SARSASAPOGENIN

作品数：8被引量：32H指数：3
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相关领域：医药卫生更多>>
相关作者：陈超李霞李冠军薛海波肖世富更多>>
相关机构：上海交通大学医学院附属精神卫生中心第三军医大学第一附属医院第三军医大学西南医院更多>>
相关期刊：《Medicinal Plant》《Acta Pharmacologica Sinica》《Journal of Systematics and Evolution》《Neuroscience Bulletin》更多>>
相关基金：国家自然科学基金更多>>
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Anti-Tumor and Anti-Diabetic Effects of Sarsasapogenin
《Medicinal Plant》2024年第1期59-61,共3页Mingxinzhi WANG Jingchao WANG Quan QUAN Xichun HUANG Xinyu LIU Chenghao JIN 
Supported by Central Talent Training Project for the Reform and Development of Local Colleges and Universities(2020GSP16);Guidance Project of Key R&D Plan in Heilongjiang Province(GZ20220039);Innovation and Entrepreneurship Training Program for College Students in Heilongjiang Province(202310223173).
In this paper,the pharmacological effects and molecular mechanisms of sarsasapogenin,such as anti-oxidant,anti-inflammatory and anti-diabetic effects,are reviewed in order to provide a theoretical basis for the subseq...
关键词：SARSASAPOGENIN ANTI-TUMOR ANTI-DIABETIC ANTI-INFLAMMATORY 
Sarsasapogenin improves adipose tissue inflammation and ameliorates insulin resistance in high-fat diet-fed C57BL/6J mice被引量：5
《Acta Pharmacologica Sinica》2021年第2期272-281,共10页Yan-yan Yu Shi-chao Cui Tian-nan Zheng Hai-jian Ma Zhi-fu Xie Hao-wen Jiang Yu-feng Li Ke-xin Zhu Cheng-gang Huang Jia Li Jing-ya Li 
supported by grants from the Ministry of Science and Technology(2018ZX09711002-018 and 2016YFC1305505)and the National Natural Science Foundation of China(81673493).
Insulin resistance is a major cause of type 2 diabetes and metabolic syndrome.Macrophage infiltration into obese adipose tissue promotes inflammatory responses that contribute to the pathogenesis of insulin resistance...
关键词：insulin resistance SARSASAPOGENIN adipose tissue inflammation macrophage-adipocyte crosstalk IKK/NF-κB JNK 
Sarsasapogenin-AA13 inhibits LPS-induced inflammatory responses in macrophage cells in vitro and relieves dimethylbenzene-induced ear edema in mice被引量：9
《Acta Pharmacologica Sinica》2017年第5期699-709,共11页Dong DONG Nan-nan ZHOU Rui-xuan LIU Jia-wei XIONG Hui PAN Si-qi SUN Lei MA Rui WANG 
Sarsasapogenin-AA13 （AA13） is a novel synthetic derivative of sarsasapogenin extracted from the Chinese herb Rhizoma Anemarrhenae. In this study we investigated the effects of AA13 on lipopolysaccharide （LPS）-indu...
关键词：SARSASAPOGENIN AA13 antifani ANTI-INFLAMMATION inflammatory factor nuclear factor-KB mitogen-activated proteinkinases ear edema 
Ribosomal DNA ITS1, 5.8S and ITS2 secondary structure, nuclear DNA content and phytochemical analyses reveal distinctive characteristics of four subclades of Protasparagus
《Journal of Systematics and Evolution》2017年第1期54-70,共17页Partha Sarathi Saha Mainak Sengupta Sumita Jha 
The use of ribosomal DNA （rDNA） internal transcribed spacer （iTS） primary sequence based phylogeny is a conventional practice to estimate the evolutionary interspecies relationship. However, analysis of the functi...
关键词：flow cytometry nuclear DNA content Protasparagus rDNA ITS secondary structure SARSASAPOGENIN Shatavarin-Ⅳ 
Identification of Gardenoside and Sarsasapogenin from Qingwen Baidu Granules by TLC
《Animal Husbandry and Feed Science》2016年第2期79-81,共3页Guo Shijin Wang Yanping Zhang Zhimei Fu shijun Xu Qianqian Zhang Ying Shen Zhiqiang 
Supported by Technical Innovation Project of Shandong Province(201210916001)
[ Objective ] We aimed to establish the identification method of gardenoside and sarsasapogenin in Qingwen baidu granules. [ Method] With ethyl ace- tate-acetone-formic acid-water （10：7：2：0.5） as the developer an...
关键词：Qingwen baidu granules Gardenoside SARSASAPOGENIN TLC identification 
A double-blind,placebo-controlled study of traditional Chinese medicine sarsasapogenin added to risperidone in patients with negative symptoms dominated schizophrenia被引量：1
《Neuroscience Bulletin》2011年第4期258-268,共11页肖世富 薛海波 李霞 陈超 李冠军 苑成梅 张明园 
supported by thegrant of Stanley Medical Research Institute(No.02I-005),USA
Objective To identify whether sarsasapogenin, a sapogenin from the Chinese medicinal herb Anemarrhena Asphodeloides Bunge, would augment the efficacy of risperidone and significantly improve cognitive functions in pat...
关键词：SCHIZOPHRENIA SARSASAPOGENIN RISPERIDONE TRIAL DOUBLE-BLIND 
A sensitive indirect competitive enzyme-linked immunosorbent assay for the detection of sarsasapogenin in rat plasma被引量：3
《Acta Pharmacologica Sinica》2010年第8期984-989,共6页Jing WANG Ji-hua LIU Xu GUO Jian ZHANG Bo-yang YU 
Aim： To generate a polyclonal antibody against sarsasapogenin and to develop an indirect competitive enzyme-linked immunosorbent assay （IC-ELISA） method for the pharmacokinetic study of Sarsasapogenin in rats. Meth...
关键词：SARSASAPOGENIN polyclonal antibody IMMUNOASSAY PHARMACOKINETICS 
Steroids from the Roots of Asparagus officinalis and Their Cytotoxic Activity被引量：15
《Journal of Integrative Plant Biology》2008年第6期717-722,共6页Xue-Feng Huang Yu-Ying Lin Ling-Yi Kong 
the National Natural Science Foundation of China (30701084);the Cultivation Fund of the Key Scientific and Technical Innovation Project, Ministry of Education of China (707033).
One new （Sarsasapogenin O） and seven known steroids were isolated from the roots of Asparagus offlcinalis L. Their structures were elucidated on the basis of spectroscopic analysis, including various 2D-NMR techniqu...
关键词：Asparagus officinalis cytotoxic activity Sarsasapogenin O STEROID 
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