IMMUNOASSAY

作品数：216被引量：366H指数：9
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Towards Improved Steroid Hormone Analysis:The Shift from Immunoassays to Mass Spectrometry
《Journal of Analysis and Testing》2025年第1期118-135,共18页Bowen Deng Mengxin Bi Yuanyuan Zheng Dilshad Hussain Sen Yang Di Chen 
China Postdoctoral Science Foundation(2021M702937)for the financial support。
Steroid hormones,synthesized from cholesterol via cytochrome P450 enzymes,are categorized into adrenocortical hormones and sex hormones.Their monitoring is crucial in clinical and research settings for evaluating dise...
关键词：Steroid hormone Sample preparation Biological sample IMMUNOASSAY Liquid chromatography-tandem mass spectrometry Gas chromatography-tandem mass spectrometry 
Electropolymerized Dopamine Film-Modified Optical Fiber LMR Biosensor for Immunoassay
《Photonic Sensors》2025年第1期138-152,共15页Xiaoshuang DAI Shuang WANG Yongle LI Junfeng JIANG Ke TAN Hongyu LIU Zhiyuan LI Tianhua XU Tiegen LIU 
supported in parts by National Key Scientific Instrument and Equipment Development Projects of China(Grant No.2022YFF0706000);National Natural Science Foundation of China(Grant No.62035006);Independent Innovation Found of Tianjin University,China(Grant No.2023XCG-0028);Tianjin Research Innovation Project for Postgraduate Students,China(Grant No.2022BKY064).
In producing high-performance optical biosensors,the selected coupling agent and its fixation mode play an essential role as one of the decisive conditions for antibody incubation.In this work,we designed optical fibe...
关键词：Optical fiber biosensor lossy mode resonance ITO electropolymerized dopamine surface functionalization 
Defect-insensitive cylindrical surface lattice resonance array and its batch replication for enhanced immunoassay
《Microsystems & Nanoengineering》2024年第6期151-160,共10页Bin Zhou Chao Hu Haoyang Li Xiangyi Ye Baohua Wen Zhangkai Zhou Jingxuan Cai Jianhua Zhou 
support from the National Key Research and Development Plan(2021YFA1400804);the National Natural Science Foundation of China(Nos.22174167,21775168,62205382);Guangdong Basic and Applied Basic Research Foundation(Nos.2021A1515110388,2024A1515011707);the Foundation of Sun Yat-sen University(No.76190-18841213);Key Basic Research Project of Shenzhen Natural Science Foundation(No.JCYJ20220818102014028);the Foundation of Guangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instrument(No.2020B1212060077).
Surface lattice resonances(SLR)have been demonstrated to enhance the sensitivity and reduce the full width at half maximum(FWHM)of the plasmonic resonances.However,their widespread application in immunoassays has been...
关键词：CYLINDRICAL insensitive RESONANCE 
Highly-Sensitive Polymer Optical Fiber SPR Sensor for Fast Immunoassay
《Photonic Sensors》2024年第4期20-30,共11页Ying WANG Xing RAO Xun WU George Y.CHEN Changrui LIAO Mateusz Jakub SMIETANA Yiping WANG 
supported by the National Natural Science Foundation of China(Grant No.62275172);Natural Science Foundation of Guangdong Province(Grant No.2023A1515012893);Science,Technology,and Innovation Commission of Shenzhen Municipality(Grant Nos.KQTD20221101093605019 and JCYJ20220818095615034);Shenzhen Key Laboratory of Ultrafast Laser Micro/Nano Manufacturing(Grant No.ZDSYS20220606100405013);Research Start-Up Fund for High-End Talent at Shenzhen University.
A new type of human immunoglobulin G(IgG)sensors based on the surface plasmon resonance(SPR)in the low refractive index(RI)plastic optical fiber(POF)and an antibody immobilization method is presented.A 50-nm-thick gol...
关键词：Optical fiber biosensor surface plasmon resonance antibody immobilization side-polished fiber plastic optical fiber 
A novel single-tube LAMP-CRISPR/Cas12b method for rapid and visual detection of zoonotic Toxoplasma gondii in the environment
《Infectious Diseases of Poverty》2024年第6期28-39,共12页Yao Liang Shi‑Chen Xie Yi‑Han Lv Yuan‑Hui He Xiao‑Nan Zheng Wei Cong Hany M.Elsheikha Xing‑Quan Zhu 
Project support is provided by the National Key Research and Develop‑ment Program of China(Grant Nos.2021YFC2300800,2021YFC2300802 and 2021YFC2300804);Shanxi Provincial Agricultural and Rural Research Program(Grant No.LXXMsxnd202101);the Research Fund of Shanxi Province for Intro‑duced High‑level Leading Talents(Grant No.RFSXIHLT202101);the Special Research Fund of Shanxi Agricultural University for High‑level Talents(Grant No.2021XG001).
Background Toxoplasma gondii oocysts,excreted in cat feces,pose a significant health risk to humans through contaminated soil and water.Rapid and accurate detection of T.gondii in environmental samples is essential fo...
关键词：Toxoplasma gondii Loop‑mediated isothermal amplifcation CRISPR/Cas12b Lateral fow immunoassay Environmental detection Zoonotic parasites Molecular diagnostics 
Progress in Procalcitonin Detection Based on Immunoassay
《Research》2024年第4期662-684,共23页Jiayue Huang Yan Zu Lexiang Zhang Wenguo Cui 
supported by the National Natural Science Foundation of China(22307098);the Zhejiang Provincial Natural Science Foundation of China(LGF22C100003);the Wenzhou high-level innovation team(Development and application team of functional liver cancer-on-a-chip);the Wenzhou Basic Research Projects(Y2023147);the Key Projects of Wenzhou Science and Technology Bureau(ZG2023013);the program of WIUCASQD2021012 from Wenzhou Institute,University of Chinese Academy of Sciences;the Scientific and Technological Innovation Major Base of Guangxi(No.2022-36-Z05).
Procalcitonin(PCT)serves as a crucial biomarker utilized in diverse clinical contexts,including sepsis diagnosis and emergency departments.Its applications extend to identifying pathogens,assessing infection severity,...
关键词：DIAGNOSIS utilized instance 
Ultrabright NIR AIEgen nanoparticles-enhanced lateral flow immunoassay platform for accurate diagnostics of complex samples
《Aggregate》2024年第4期308-318,共11页Jia Shu Yujian Li Huan Cai Qing Fu Chunyang Li Jianbo Yuan Yan Zhao Changjin Liu Haiping Wu Doudou Ling Zhangluxi Liu Guannan Su Qingfeng Cao Xiaolin Huang Rui Chen Peizeng Yang 
National Natural Science Foundation of China,Grant/Award Numbers:82202642,82302646,32172296;Chongqing Postdoctoral Innovation Talent Support Program,Grant/Award Number:CQBX202218;China Postdoctoral Science Foundation,Grant/Award Numbers:2022M710558,2023T160771;Special foundation of Chongqing Postdoctoral Research Programme,Grant/Award Number:2021XM2036;Talent Training Foundation of Key Laboratory of Clinical Laboratory Diagnostics(Ministry of Education)of College of Laboratory Medicine,Grant/Award Number:JYPY202202;Chongqing Postdoctoral Science Foundation,Grant/Award Number:CSTB2022NSCQ-BHX0689;National Natural Science Foundation Key Program,Grant/Award Numbers:82230032,81930023;Key Project of Chongqing Science and Technology Bureau,Grant/Award Number:CSTC2021jscx-gksb-N0010;Chongqing Outstanding Scientists Project(2019);Chongqing Chief Medical Scientist Project(2018);Chongqing Science and Technology Bureau Mountaineering Project,Grant/Award Numbers:cyyy-xkdfjh-jcyj-202301,cyyy-xkdfjh-lcyj-202303,cyyy-xkdfjh-cgzh-202302。
Accurate and sensitive near-infrared(NIR)luminescent lateralflow immunoassay(LFIA)has attracted considerable attention in thefield of point-of-care testing(POCT).However,the detection accuracy and sensitivity are ofte...
关键词：aggregation-induced emission complex sample lateralflow immunoassay NEAR-INFRARED rapid diagnostic testing 
BCAR3 and BCAR3-related competing endogenous RNA expression in hepatocellular carcinoma and their prognostic value
《World Journal of Gastrointestinal Oncology》2024年第7期3082-3096,共15页Hui-Qin Shi Shu Huang Xin-Yue Ma Zhen-Ju Tan Rui Luo Bei Luo Wei Zhang Lei Shi Xiao-Lin Zhong Mu-Han Lü Xia Chen Xiao-Wei Tang 
BACKGROUND Hepatocellular carcinoma(HCC)is a malignant tumor that has a high incidence and mortality worldwide.Despite extensive studies,the detailed molecular mechanism of HCC development remains unclear.Studies have...
关键词：Hepatocellular carcinoma Breast cancer anti-estrogen-resistant protein 3 BIOINFORMATICS Prognosis IMMUNOASSAY 
Prozone and postzone effect:Unravelling the issues and designing a protocol to address hook effect in immunoassays
《LabMed Discovery》2024年第2期104-108,共5页Ashraf Mina Leah McNeice Shanmugam Banukumar Santiago Vazquez 
The hook effect is best explained by how the analyte signal generated from the assay is compromised due to either antibody excess or antigen excess.Reporting false negatives can also impact clinical decisions that may...
关键词：Hook effect Postzone effect Prozone effect IMMUNOASSAY 
Nanobody-based food allergen surveillance:current status and prospects
《Food Quality and Safety》2024年第2期227-238,共12页Yi Wang Sihao Wu Ang Li Huan Lv Xuemeng Ji Yaozhong Hu Shuo Wang 
funded by the National Natural Science Foundation of China(No.32272403);the National Key Research and Development Program of China(No.2022YFF1102400).
The incidence of food allergy has increased in recent decades,posing drastic risks to sensitive individuals,leading to mild to severe allergic symptoms.There is still no effective immune therapeutic strategy for food ...
关键词：Food allergy food allergen NANOBODY IMMUNOASSAY 
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