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The development and application of the mobile frailty management platform for Chinese community-dwelling older adults
《International Journal of Nursing Sciences》2025年第2期115-122,I0001,共9页Jjiayi Hou Xinrui Wan Mengjie Li Gujuan He 
Objectives:This study aimed to develop a mobile frailty management platform for Chinese communitydwelling older adults and evaluate its effectiveness,usability and safety.Methods:Based on literature research,the resea...
关键词：COMMUNITY FRAILTY Mobile health Older adults Quasi-experimental trial Qualityof life Sleep quality 
Radial artery deviation and reimplantation technique vs classical technique in arterio-venous fistula:A randomised control trial
《World Journal of Nephrology》2025年第2期139-146,共8页Shakti S Sarangi Shashank Kumar Deepak P Bhirud Mahendra Singh Shiv C Navriya Gautam Ram Choudhary Arjun Singh Sandhu 
BACKGROUND Surgically created arterio-venous fistulas(AVFs)are the gold standard for haemodialysis access for patients with end-stage renal disease.Standard practice of AVF creation involves selecting the non-dominant...
关键词：Radial artery deviation and reimplantation technique Classical technique Arterio-venous fistula Arterio-venous fistula trial Dialysis fistula Chronic kidney disease 
A comprehensive step-by-step approach for the implementation of target trial emulation:Evaluating fluid resuscitation strategies in post-laparoscopic septic shock as an example
《Laparoscopic, Endoscopic and Robotic Surgery》2025年第1期28-44,共17页Jie Yang Lihui Wang Lin Chen Pengmin Zhou Suibi Yang Hongjie Shen Lifeng Xing Pengpeng Chen Yuetian Yu Hongying Ni Zhongheng Zhang 
Zhongheng Zhang received funding from the National Natural Science Foundation of China(82272180,82472243);the China National Key Research and Development Program(2023YFC3603104);the Huadong Medicine Joint Funds of the Zhejiang Provincial Natural Science Foundation of China(LHDMD24H150001);the China National Key Research and Development Program(2022YFC2504500);a collaborative scientific project co-established by the Science and Technology Department of the National Administration of Traditional Chinese Medicine and the Zhejiang Provincial Administration of Traditional Chinese Medicine(GZY-ZJKJ-24082);the General Health Science and Technology Program of Zhejiang Province(2024KY1099);Project of Zhejiang University Longquan Innovation Center(ZJDXLQCXZCJBGS2024016);Hongying Ni received funding from Jinhua Science and Technology Planning Project(2024-3-047).
Objective:To develop and demonstrate a comprehensive methodological framework for target trial emulation(TTE)implementation via post-laparoscopic septic shock fluid management as a clinical case study.Methods:We desig...
关键词：Laparoscopic surgery SEPSIS Target trial emulation 
Chirped solutions and dynamical properties of the resonant Schr?dinger equation with quadratic-cubic nonlinearity
《Applied Mathematics(A Journal of Chinese Universities)》2025年第1期223-237,共15页TANG Jia-xuan 
In this paper, the nonlinear Schr?dinger equation combining quadratic-cubic nonlinearity is considered, which can be represented by an approximate model of relatively dense quasi-one-dimensional Bose-Einstein condensa...
关键词：chirped solutions bifurcation theory trial equation method quadratic-cubic nonlinearity non-linear waves 
Effects of ADIET communication and delivery rehearsal on anxiety,labor process,and outcomes in vaginal trial delivery
《World Journal of Psychiatry》2025年第3期186-192,共7页Ling-Mei Liu Hao-Yu He Jing-Xian Lu 
In recent years,the obstetrics department has advocated vaginal delivery to reduce the rate of cesarean sections.However,in clinical practice,pregnant women are prone to anxiety before childbirth,making it difficult t...
关键词：Greeting-self-introduction-process-explanation-thanks for communication Labor rehearsal Vaginal trial Prenatal anxiety LABOR Labor outcome 
Safety and efficacy of selective RIPK1 inhibitor SIR1-365 in hospitalized patients with severe COVID-19:A multicenter,randomized,double-blind,phase 1b trial
《Journal of Intensive Medicine》2025年第1期70-78,共9页Norberto Chavez-Tapia Muneeba Ahsan Sayeed Shobha Luxmi Douglas J.Kasper Fenchao Xue Yang Shen Weiliang Fan Wei Yuan Bin Du 
Background:Receptor-interacting protein kinase 1(RIPK1),a serine/threonine protein kinase,is mainly activated by pro-inflammatory cytokines and pathogens,including severe acute respiratory syndrome coronavirus 2(SARS-...
关键词：COVID-19 Phase 1b trial Receptor-interacting protein 1 RIPK1 RIPK1 inhibitor SIR1-365 
Prophylactic hyperthermic intraperitoneal chemotherapy in patients with locally advanced gastric cancer after curative surgery:Final results of a phase Ⅱ trial
《Chinese Journal of Cancer Research》2025年第1期66-72,共7页Biao Fan Hao Su Lingqian Wang Xin Ji Yinan Zhang Ziyu Jia Ji Zhang Zhaode Bu Xiaojiang Wu 
supported by the National Nature Science Foundation of China(No.81402308);Science Foundation of Peking University Cancer Hospital(No.2021-24);Natural Science Foundation of Beijing Municipal(No.7242020);Science Foundation of Peking University Cancer Hospital(No.BJCH2025GG04);the National Nature Science Foundation of China(No.82173151).
Objective:The trial was designed to evaluate the efficacy of prophylactic hyperthermic intraperitoneal chemotherapy(HIPEC)with cisplatin for patients with locally advanced gastric cancer(LAGC).Methods:Between March 20...
关键词：Gastric cancer intraperitoneal chemotherapy CISPLATIN PROGNOSIS 
Trial-Manufacture and Experimental Study of Particle Damping Boring Bar for Deep Hole Boring of 7075 Aluminum Alloy
《Transactions of Nanjing University of Aeronautics and Astronautics》2025年第1期123-136,共14页HUANG Yi HAN Jianxin DONG Qingyun 
supported by the Scientific Research Program of Tianjin Education Committee(No.2022ZD030)。
7075 aluminum alloy is often used as an important load-bearing structure in aircraft industry due to its superior mechanical properties.During the process of deep hole boring,the boring bar is prone to vibrate because...
关键词：7075 aluminum alloy boring bar vibration reduction particle damping 
Efficacy and safety of lenvatinib plus gefitinib in lenvatinibresistant hepatocellular carcinomas: a prospective, single-arm exploratory trial
《Signal Transduction and Targeted Therapy》2025年第1期314-320,共7页Yaoping Shi Dan Cui Lei Xia Donghua Shi Guangxin Jin Siying Wang Yan Lin Xiaoyin Tang Jiachang Chi Tao Wang Meng Li Zicheng Lv Jiaojiao Zheng Qi Jia Wu Yang Zhen Sun Fan Yang Hao Feng Shengxian Yuan Weiping Zhou Wenxin Qin Rene Bernards Haojie Jin Bo Zhai 
supported by the National Natural Science Foundation(Nos.82222047,82073039,82330095,81502672,and 82070619);the Program of Shanghai Academic/Technology Research Leader(No.22XD1423100);the National Key Research and Development Program of China(2022YFC2804300);Shanghai Municipal Commission of Health and Family Planning(2022XD057);the Shanghai Committee of Science and Technology(23ZR1439000 and 22S11900500).
Lenvatinib,a multi-kinase inhibitor,has been approved asfirst-line treatment for advanced hepatocellular carcinoma(HCC),but its efficacy is limited.We have shown previously that lenvatinib and epidermal growth factor ...
关键词：GEFITINIB DIARRHEA treatment 
Alternating modified CAPOX/CAPIRI plus bevacizumab in untreated unresectable metastatic colorectal cancer:a phase 2 trial
《Signal Transduction and Targeted Therapy》2025年第1期321-327,共7页Sheng Li Xiaoyou Li Hanfeng Xu Jiayuan Huang Jingni Zhu Ying Peng Jun Bao Liangjun Zhu 
supported by Beijing Science and Technology Innovation Medical Development Foundation(grant no.KC2021-JX-0186-106).
Previous studies showed encouraging efficacy of alternating FOLFOX/FOLFIRI for metastatic colorectal cancer(mCRC).This phase 2 trial(NCT04324476)aimed to evaluate efficacy and safety of alternating modified CAPOX(cape...
关键词：BEVACIZUMAB UNTREATED COLORECTAL 
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