云南高校图书馆联盟文献共享服务平台- TRIAL

检索规则说明：AND代表“并且”；OR代表“或者”；NOT代表“不包含”；(注意必须大写,运算符两边需空一格)

检索范例：范例一： (K=图书馆学 OR K=情报学) AND A=范并思　　　　范例二：J=计算机应用与软件 AND (U=C++ OR U=Basic) NOT M=Visual

全部期刊核心期刊 EI来源期刊 SCI来源期刊 CA来源期刊 CSCD来源期刊 CSSCI来源期刊

A comprehensive step-by-step approach for the implementation of target trial emulation:Evaluating fluid resuscitation strategies in post-laparoscopic septic shock as an example: 《Laparoscopic, Endoscopic and Robotic Surgery》2025年第1期28-44,共17页Jie Yang Lihui Wang Lin Chen Pengmin Zhou Suibi Yang Hongjie Shen Lifeng Xing Pengpeng Chen Yuetian Yu Hongying Ni Zhongheng Zhang; Zhongheng Zhang received funding from the National Natural Science Foundation of China(82272180,82472243);the China National Key Research and Development Program(2023YFC3603104);the Huadong Medicine Joint Funds of the Zhejiang Provincial Natural Science Foundation of China(LHDMD24H150001);the China National Key Research and Development Program(2022YFC2504500);a collaborative scientific project co-established by the Science and Technology Department of the National Administration of Traditional Chinese Medicine and the Zhejiang Provincial Administration of Traditional Chinese Medicine(GZY-ZJKJ-24082);the General Health Science and Technology Program of Zhejiang Province(2024KY1099);Project of Zhejiang University Longquan Innovation Center(ZJDXLQCXZCJBGS2024016);Hongying Ni received funding from Jinhua Science and Technology Planning Project(2024-3-047).; Objective:To develop and demonstrate a comprehensive methodological framework for target trial emulation(TTE)implementation via post-laparoscopic septic shock fluid management as a clinical case study.Methods:We desig...; 关键词：Laparoscopic surgery SEPSIS Target trial emulation

Chirped solutions and dynamical properties of the resonant Schr?dinger equation with quadratic-cubic nonlinearity: 《Applied Mathematics(A Journal of Chinese Universities)》2025年第1期223-237,共15页TANG Jia-xuan; In this paper, the nonlinear Schr?dinger equation combining quadratic-cubic nonlinearity is considered, which can be represented by an approximate model of relatively dense quasi-one-dimensional Bose-Einstein condensa...; 关键词：chirped solutions bifurcation theory trial equation method quadratic-cubic nonlinearity non-linear waves

Effects of ADIET communication and delivery rehearsal on anxiety,labor process,and outcomes in vaginal trial delivery: 《World Journal of Psychiatry》2025年第3期186-192,共7页Ling-Mei Liu Hao-Yu He Jing-Xian Lu; In recent years,the obstetrics department has advocated vaginal delivery to reduce the rate of cesarean sections.However,in clinical practice,pregnant women are prone to anxiety before childbirth,making it difficult t...; 关键词：Greeting-self-introduction-process-explanation-thanks for communication Labor rehearsal Vaginal trial Prenatal anxiety LABOR Labor outcome

Safety and efficacy of selective RIPK1 inhibitor SIR1-365 in hospitalized patients with severe COVID-19:A multicenter,randomized,double-blind,phase 1b trial: 《Journal of Intensive Medicine》2025年第1期70-78,共9页Norberto Chavez-Tapia Muneeba Ahsan Sayeed Shobha Luxmi Douglas J.Kasper Fenchao Xue Yang Shen Weiliang Fan Wei Yuan Bin Du; Background:Receptor-interacting protein kinase 1(RIPK1),a serine/threonine protein kinase,is mainly activated by pro-inflammatory cytokines and pathogens,including severe acute respiratory syndrome coronavirus 2(SARS-...; 关键词：COVID-19 Phase 1b trial Receptor-interacting protein 1 RIPK1 RIPK1 inhibitor SIR1-365

Trial-Manufacture and Experimental Study of Particle Damping Boring Bar for Deep Hole Boring of 7075 Aluminum Alloy: 《Transactions of Nanjing University of Aeronautics and Astronautics》2025年第1期123-136,共14页HUANG Yi HAN Jianxin DONG Qingyun; supported by the Scientific Research Program of Tianjin Education Committee(No.2022ZD030)。; 7075 aluminum alloy is often used as an important load-bearing structure in aircraft industry due to its superior mechanical properties.During the process of deep hole boring,the boring bar is prone to vibrate because...; 关键词：7075 aluminum alloy boring bar vibration reduction particle damping

Efficacy and safety of lenvatinib plus gefitinib in lenvatinibresistant hepatocellular carcinomas: a prospective, single-arm exploratory trial: 《Signal Transduction and Targeted Therapy》2025年第1期314-320,共7页Yaoping Shi Dan Cui Lei Xia Donghua Shi Guangxin Jin Siying Wang Yan Lin Xiaoyin Tang Jiachang Chi Tao Wang Meng Li Zicheng Lv Jiaojiao Zheng Qi Jia Wu Yang Zhen Sun Fan Yang Hao Feng Shengxian Yuan Weiping Zhou Wenxin Qin Rene Bernards Haojie Jin Bo Zhai; supported by the National Natural Science Foundation(Nos.82222047,82073039,82330095,81502672,and 82070619);the Program of Shanghai Academic/Technology Research Leader(No.22XD1423100);the National Key Research and Development Program of China(2022YFC2804300);Shanghai Municipal Commission of Health and Family Planning(2022XD057);the Shanghai Committee of Science and Technology(23ZR1439000 and 22S11900500).; Lenvatinib,a multi-kinase inhibitor,has been approved asfirst-line treatment for advanced hepatocellular carcinoma(HCC),but its efficacy is limited.We have shown previously that lenvatinib and epidermal growth factor ...; 关键词：GEFITINIB DIARRHEA treatment

Alternating modified CAPOX/CAPIRI plus bevacizumab in untreated unresectable metastatic colorectal cancer:a phase 2 trial: 《Signal Transduction and Targeted Therapy》2025年第1期321-327,共7页Sheng Li Xiaoyou Li Hanfeng Xu Jiayuan Huang Jingni Zhu Ying Peng Jun Bao Liangjun Zhu; supported by Beijing Science and Technology Innovation Medical Development Foundation(grant no.KC2021-JX-0186-106).; Previous studies showed encouraging efficacy of alternating FOLFOX/FOLFIRI for metastatic colorectal cancer(mCRC).This phase 2 trial(NCT04324476)aimed to evaluate efficacy and safety of alternating modified CAPOX(cape...; 关键词：BEVACIZUMAB UNTREATED COLORECTAL

Toripalimab plus chemotherapy for first line treatment of advanced non-small cell lung cancer (CHOICE-01): final OS and biomarker exploration of a randomized, double-blind, phase 3 trial: 《Signal Transduction and Targeted Therapy》2025年第1期411-419,共9页Jia Zhong Kailun Fei Lin Wu Baolan Li Zhijie Wang Ying Cheng Xiaoling Li Xicheng Wang Liang Han Xiaohong Wu Yun Fan Yan Yu Dongqing Lv Jianhua Shi Jianjin Huang Shaozhang Zhou Baohui Han Guogui Sun Qisen Guo Youxin Ji Xiaoli Zhu Sheng Hu Wei Zhang Qiming Wang Yuming Jia Ziping Wang Yong Song Jingxun Wu Meiqi Shi Xingya Li Zhigang Han Yunpeng Liu Zhuang Yu An-Wen Liu Xiuwen Wang Caicun Zhou Diansheng Zhong Liyun Miao Zhihong Zhang Hui Zhao Jun Yang Dong Wang Yingyi Wang Qiang Li Xiaodong Zhang Mei Ji Zhenzhou Yang Jiuwei Cui Beili Gao Buhai Wang Hu Liu Lei Nie Mei He Shi Jin Wei Gu Yongqian Shu Tong Zhou Jian Feng Xinmei Yang Cheng Huang Bo Zhu Yu Yao Sheng Yao Jianjun Yu Shang li Cai Yiran Cai Jiachen Xu Wei Zhuang Xianmin Luo Jianchun Duan Jie Wang; supported by National key R&D program of China(2022YFC2505000)to J.W;NSFC general program(82272796)NSFC special program(82241229)to J.W;CAMS Innovation Fund for Medical Sciences(CIFMS 20adjuvant-I2M-1-009)to J.W,CAMS Key Laboratory of Translational Research on Lung Cancer(2018PT31035)to J.W;Aiyou foundation(KY201701)to J.W,CAMS Innovation Fund for Medical Sciences(2021-1-I2M-012)to Z.W.Beijing Natural Science Foundation(7222144)to J.Z,NSFC program(82303969)to J.Z.; A randomized double-blind phase 3 trial(CHOICE-01,NCT03856411)demonstrated that combining toripalimab with chemotherapy substantially improves progression-free survival(PFS)in advanced non-small cell lung cancer(NSCLC...; 关键词：double TREATMENT utilizing

Efficacy and safety of minocycline in retinitis pigmentosa:a prospective,open-label,single-arm trial: 《Signal Transduction and Targeted Therapy》2025年第1期271-277,共7页Yuxi Chen Yuan Pan Yanyan Xie Yuxun Shi Yao Lu Yiwen Xia Wenru Su Xiaoqing Chen Zuoyi Li Minzhen Wang Siyu Miao Yating Yang Chenjin Jin Guangwei Luo Shixian Long Hui Xiao Chuangxin Huang Jian Zhang Dan Liang; supported by the Sun Yat-sen University Clinical Research 5010 Program(2018012).; Retinitis pigmentosa(RP)is characterized by progressive photoreceptor cells death accelerated by the proliferation and activation of microglia pathologically.No consensus exists on the treatment.Minocycline is recogni...; 关键词：protective PROSPECTIVE adapted

Anlotinib plus chemotherapy as afirst-line treatment for gastrointestinal cancer patients with unresectable liver metastases:a multicohort,multicenter,exploratory trial: 《Signal Transduction and Targeted Therapy》2025年第1期303-313,共11页Jun-Wei Wu Chen-Fei Zhou Zheng-Xiang Han Huan Zhang Jun Yan Jun Chen Chun-Bin Wang Zhi-Quan Qin Yong Mao Xin-Yu Tang Liang-Jun Zhu Xiao-Wei Wei Dong-Hai Cui Xiu-Li Yang Min Shi Li-Qin Zhao Jin-Ling Jiang Wei-You Zhu Hong-Mei Wang Chun Wang Ling-Jun Zhu Jun Zhang; supported by the National Natural Science Foundation of China(82273126 and 82273407);the Collaborative Innovation Cluster Project of the Shanghai Municipal Health Commission(grant number,2020CXJQ03);the Innovative research teams of high-level local universities in Shanghai.The authors thank all patients,their families,investigators,and research staffs for participating in this trial.; This multicohort phase II trial(ALTER-G-001;NCT05262335)aimed to assess the efficacy offirst-line anlotinib plus chemotherapy for gastrointestinal(GI)cancer patients with unresectable liver metastases.Eligible patient...; 关键词：patients METASTASES GASTROINTESTINAL

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

TRIAL

检索结果分析

下载全文

高级检索检索式检索

时间限定

期刊范围

学科限定全选

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

TRIAL

检索结果分析

下载全文

用户登录

高级检索检索式检索