INTERLEUKIN-23

作品数:25被引量:170H指数:8
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相关领域:医药卫生更多>>
相关作者:匡希斌廖雯婷蒋娜张道福程雪更多>>
相关机构:南华大学南方医科大学山东省地方病防治研究所安徽中医药大学更多>>
相关期刊:《World Journal of Immunology》《Chinese Medical Journal》《安徽中医药大学学报》《中国实用医刊》更多>>
相关基金:国家自然科学基金上海市自然科学基金国家重点基础研究发展计划更多>>
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HIF-1α and MIF enhance neutrophil-driven type 3 immunity and chondrogenesis in a murine spondyloarthritis model
《Cellular & Molecular Immunology》2024年第7期770-786,共17页Akihiro Nakamura Sungsin Jo Sayaka Nakamura Mansi K.Aparnathi Shaghayegh Foroozan Boroojeni Mariia Korshko Ye-Soo Park Himanshi Gupta Sandra Vijayan Jason S.Rockel Mohit Kapoor Igor Jurisica Tae-Hwan Kim Nigil Haroon 
supported by grants to NH from the Canadian Institute of Health Research(CIHR)and Arthritis Society(Canada);AN is a recipient of a CIHR fellowship,Spondyloarthritis Research and Treatment Network(SPARTAN)fellowship,Spondyloarthritis Research Consortium of Canada(SPARCC)fellowship,Edward Christie Stevens fellowship;S.Fenwick Research fellowship,and Krembil Research Institute fellowship(Canada);IJ was supported in part by funding from the Natural Sciences Research Council(NSERC#203475);Canada Foundation for Innovation(CFI#225404,#30865);Ontario Research Fund(RDI#34876,RE010-020);IBM and Ian Lawson van Toch Fund.THK was supported by funding from the National Research Foundation(NRF)of Korea(NRF-2021R1A6A1A03038899);the Korea Healthy Industry Development Institute(HI23C0661).
The hallmarks of spondyloarthritis(SpA)are type 3 immunity-driven inflammation and new bone formation(NBF).Macrophage migration inhibitory factor(MIF)was found to be a key driver of the pathogenesis of SpA by amplifyi...
关键词:Endochondral ossification Hypoxia-inducible factor-1 alpha INTERLEUKIN-23 Macrophage migration inhibitory factor NEUTROPHIL SPONDYLOARTHRITIS 
Approach to loss of response to advanced therapies in inflammatory bowel disease被引量:1
《World Journal of Gastroenterology》2024年第22期2902-2919,共18页Nikil Vootukuru Abhinav Vasudevan 
BACKGROUND Remarkable progress over the last decade has equipped clinicians with many options in the treatment of inflammatory bowel disease.Clinicians now have the unique opportunity to provide individualized treatme...
关键词:Inflammatory bowel disease Ulcerative colitis CROHN BIOLOGICS Interleukin-12 and interleukin-23 inhibitors Alpha-beta7-integrin inhibitors Janus kinase inhibitors Sphingosine-1-phosphate receptor modulators 
Mechanism of intervention of medicine combined with mild moxibustion on hypothyroidism rat model
《Journal of Hainan Medical University》2023年第4期46-51,共6页WANG Hong-yang SUN Jia-zi LIU Qing-qing YAN Jing ZHANG Tian-sheng HAO Chong-yao 
Shanxi Provincial Natural Science Foundation Project(202203021211083);College Science and Technology Innovation Project of Shanxi Provincial Education Department(2020L044);Graduate Innovation Program of Shanxi University of Traditional Chinese Medicine(2021CX035)。
Objective:To explore the intervention effect of medicine combined with mild moxibustion on immune factor and Na/I symporter(NIS)in hypothyroidism rat model.Methods:The model was successfully made by intragastric admin...
关键词:HYPOTHYROIDISM INTERLEUKIN-4 INTERLEUKIN-23 Na/I symporter Medicine combined with mild moxibustion 
High IL-23^(+)cells infiltration correlates with worse clinical outcomes and abiraterone effectiveness in patients with prostate cancer被引量:2
《Asian Journal of Andrology》2022年第2期147-153,共7页Zheng Liu Jun-Yu Zhang Yun-Jie Yang Kun Chang Qi-Feng Wang Yun-Yi Kong Bo Dai 
This study was supported by grant from the National Key R&D Program of China(2017YFC0114303);grant from the Natural Science Foundation of Science and Technology Commission of Shanghai Municipality(20ZR1412300);grant from the Medical Innovation Research Project of the Science and Technology Commission of Shanghai Municipality(No.20Y11905000);grants from the AoXiang Project of the Shanghai Anti-Cancer Association(SACA-AX201908 and SACA-AX202005);All these study sponsors have no roles in the study design,collection,analysis,and interpretation of data.
Individualized treatment of prostate cancer depends on an accurate stratification of patients who are sensitive to various treatments.Interleukin-23(IL-23)was reported to play a significant role in prostate cancer.Her...
关键词:abiraterone acetate INTERLEUKIN-23 prognosis prostate cancer 
Risk of hepatitis B virus reactivation in patients with autoimmune diseases undergoing non-tumor necrosis factor-targeted biologics被引量:8
《World Journal of Gastroenterology》2021年第19期2312-2324,共13页Shintaro Akiyama Thomas G Cotter Atsushi Sakuraba 
Hepatitis B virus reactivation(HBVr)can occur in patients treated with immunosuppressive medications.Risk stratification for HBVr based on hepatitis B virus(HBV)serology and viral load is an important strategy to dete...
关键词:Hepatitis B virus Autoimmune diseases Biological therapy INTERLEUKIN-23 INTERLEUKIN-17 Janus kinases 
Expression of toll-like receptor 4 gene polymorphism and inflammatory factors in peripheral blood on patients with sepsis
《Discussion of Clinical Cases》2020年第4期15-21,共7页Tieying Tian Xiyuan Xu Jingping Yang 
Objective:To observe the presence of toll-like receptor 4(TLR4)gene polymorphism in the venous blood in patients with sepsis,meanwhile,to observe the expression and the diagnostic value of TLR4 mRNA,interferon-(IFN-),...
关键词:SEPSIS Toll-like receptor 4 INTERLEUKIN-23 Gene polymorphism 
Daifan San intervenes in forkhead box P3 and the interleukin(IL)-23/IL-17A signaling pathway to help prevent and treat primary biliary cirrhosis被引量:4
《Journal of Traditional Chinese Medicine》2020年第4期571-583,共13页Zhan Kai Xu Yan Han Mengling Cheng Liangbin 
The Science and Technology Bureau of Wuhan,China(No.2015061701011646);the Key Projects of the Hubei Provincial Education Department(No.D20112001)。
OBJECTIVE:To investigate the mechanism by which Daifan San(DFS)prevents and treats primary biliary cirrhosis(PBC)via the forkhead box P3(FoxP3)and interleukin(IL)-23/IL-17A signaling pathways.METHODS:Ninety C57BL/6 mi...
关键词:Liver cirrhosis biliary INTERLEUKIN-23 INTERLEUKIN-17 Signal transduction FoxP3 protein mouse Daifan San 
Effect of interleukin-23 on inflammation response and oxidative stress in rats with myocardial ischemia reperfusion injury
《Journal of Hainan Medical University》2017年第19期1-6,共6页Kai Zhang Wei-Pan Xu Dao-Qun Jin Zhi-Qiang Chen Xiao-Rong Hu 
Hubei Natural Science Foundation of China(2015CFB701).
Objective: To investigate the effect of interleukin-23 (IL-23) on myocardial ischemia-reperfusion (I/R) injury.Methods: Male Sprague-Dawley rats were randomly assigned into sham operated control (SO) group, ischemia a...
关键词:INTERLEUKIN-23 INFLAMMATORY responses OXIDATIVE stress MYOCARDIAL ISCHEMIA and REPERFUSION 
孟鲁司特钠对毛细支气管炎患儿IL-17和IL-23表达的影响被引量:1
《中国实用医刊》2017年第13期86-88,共3页张向峰 常会娟 张小宁 余燕娟 李晓燕 靳秀红 
目的 探讨孟鲁司特钠应用在毛细支气管炎患儿中的临床疗效及应用价值.方法 将110例毛细支气管炎患儿采用随机数字表法分为观察组和对照组,每组55例,对照组给予西医常规治疗,观察组联合孟鲁司特钠治疗,记录两组治疗情况.结果 观察组干预...
关键词:孟鲁司特钠 毛细支气管炎 白细胞介素-17 白细胞介素-23 INTERLEUKIN-17 INTERLEUKIN-23 
脑脊液腺苷脱氨酶、白介素23联合检测在结核性脑膜炎相关疾病诊断中的临床价值被引量:8
《中国基层医药》2017年第3期435-438,共4页汪春雷 张道福 孙金龙 
目的:探讨脑脊液腺苷脱氨酶(ADA)、白介素23(IL-23)联合检测在结核性脑膜炎相关疾病诊断中的临床应用价值。方法选择结核性脑膜炎相关疾病患者253例为研究对象,按诊断分为结核性脑膜炎组(脑膜炎组)138例、结核性脑膜炎合并脑积...
关键词:脑膜炎 结核性 脑积水 腺苷脱氨酶 白细胞介素23 INTERLEUKIN-23 
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