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BIOLOGICS: 作品数：96被引量：294H指数：8; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：钱齐宏李敏更多>>; 相关机构：上海工业生物技术研发中心苏州大学更多>>; 相关期刊：《Chinese Journal of Integrative Medicine》《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《World Journal of Gastrointestinal Pharmacology and Therapeutics》更多>>; 相关基金：国家自然科学基金更多>>

Uveitis associated with juvenile idiopathic arthritis and chronic idiopathic uveitis in children:A retrospective cohort study: 《World Journal of Clinical Pediatrics》2025年第2期56-68,共13页Alexandr Alexandrovich Yakovlev Ekaterina Vladimirovna Gaidar Lyubov Sergeevna Sorokina Tatiana Nikolaevna Nikitina Olga Valerievna Kalashnikova Mikhail Mikhailovich Kostik; BACKGROUND Chronic idiopathic uveitis(CIU)and juvenile idiopathic arthritis-associated uveitis(U-JIA)are both vision-threatening conditions that share similar autoimmune mechanisms,but treatment approaches differ sign...; 关键词：UVEITIS Juvenile idiopathic arthritis IRIDOCYCLITIS Anterior uveitis Idiopathic uveitis BIOLOGICS Cohort study

Biologics in the management of pediatric inflammatory bowel disease:When and what to choose: 《World Journal of Clinical Pediatrics》2025年第1期21-45,共25页Arghya Samanta Anshu Srivastava; Pediatric inflammatory bowel disease(PIBD)is a chronic inflammatory disorder of the gastrointestinal tract,with rising global incidence and prevalence.Over the past two decades,biologics have added to the therapeutic ...; 关键词：BIOLOGICS CHILDREN Inflammatory bowel disease Therapeutic drug monitoring Dual biologic

Effectiveness of biologics for endoscopic healing in patients with isolated proximal small bowel Crohn’s disease: 《World Journal of Gastroenterology》2025年第7期39-50,共12页Zi-Cheng Huang Bi-Yao Wang Bo Peng Zhong-Cheng Liu Hui-Xian Lin Qing-Fan Yang Jian Tang Kang Chao Miao Li Xiang Gao Qin Guo; Supported by the Program of Guangdong Provincial Clinical Research Center for Digestive Diseases,No.2020B1111170004.; BACKGROUND Endoscopic healing(EH)is a key therapeutic target in Crohn’s disease(CD).Proximal small bowel(SB)lesions in patients with CD are associated with a significant risk of strictures and bowel resection.Assessi...; 关键词：Crohn’s disease Isolated proximal small bowel disease Endoscopic healing BIOLOGICS Balloon-assisted enteroscopy

New perspectives and prospects for the next generation of combination therapy in inflammatory bowel disease: 《World Journal of Gastroenterology》2025年第5期124-128,共5页Wen-Ting Xie Hui Yang Lan Bai Feng-Fei Wu; Supported by the National Natural Science Foundation of China,No.82400591(to Wu FF).; This article comments on the letter by Lowell et al,which addresses the next generation of combination therapy for inflammatory bowel disease(IBD).As the understanding of the pathogenesis of IBD continues to improve,t...; 关键词：Inflammatory bowel disease BIOLOGICS Dual-biologic therapy Supportive treatment The next generation of combination therapy

Real-world experience and long-term outcomes of a mandatory nonmedical switch of adalimumab originator to biosimilars in inflammatory bowel disease: 《World Journal of Gastroenterology》2024年第46期4904-4913,共10页Jeremy Liu Chen Kiow Thomas Hoang Harjot K Bedi Zhina Majdzadeh Ardekani Daniel Rosenfeld Marica Reise-Filteau Brian Bressler Yvette Leung Greg Rosenfeld; BACKGROUND Over the last decade,the treatment options for inflammatory bowel disease(IBD)have significantly progressed with the emergence of new medications designed to target various immune pathways and mitigate infl...; 关键词：Inflammatory bowel disease Ulcerative colitis Crohn’s disease BIOLOGICS ADALIMUMAB Biosimilar switch

Refractory ulcerative colitis:Upadacitinib versus other biologics: 《World Journal of Clinical Cases》2024年第31期6425-6427,共3页Said G Farhat Jessy G Fadel; In this editorial we comment on an article published in World Journal of Clinical Cases in 2024,in which a case of refractory ulcerative colitis(UC)was discussed based on the response to different lines of biologics.D...; 关键词：REFRACTORY Ulcerative colitis Upadacitinib USTEKINUMAB Vedolizumab

Navigating the complexities of perianal Crohn’s disease:Diagnostic strategies,treatment approaches,and future perspectives: 《World Journal of Gastroenterology》2024年第44期4745-4753,共9页Jai P Singh Maryam Aleissa Ernesto R Drelichman Vijay K Mittal Jasneet S Bhullar; This article discusses the literature review article by Pacheco et al published in July 2024;the authors provided good reviews of perianal Crohn’s disease(CD),and challenges faced by clinicians in the management.CD,c...; 关键词：Crohn’s disease PERIANAL FISTULA FISTULOTOMY BIOLOGICS Stem cell therapy

Anti-stroke biologics:from recombinant proteins to stem cells and organoids: 《Stroke & Vascular Neurology》2024年第5期467-480,共14页Zhu-Wei Miao Zhi Wang Si-Li Zheng Shu-Na Wang Chao-Yu Miao; National Natural Science Foundation of China(82030110 and 82330117 to C-YM,82104166 to ZW).; The use of biologics in various diseases has dramatically increased in recent years.Stroke,a cerebrovascular disease,is the second most common cause of death,and the leading cause of disability with high morbidity wor...; 关键词：DOSAGE ROUTINE treatment

Oral administration microrobots for drug delivery: 《Bioactive Materials》2024年第9期163-190,共28页An Ren Jiarui Hu Changwei Qin Neng Xia Mengfei Yu Xiaobin Xu Huayong Yang Min Han Li Zhang Liang Ma; the funding from National Key Research and Development Program of China,China(No.2018YFA0703000);The National Natural Science Foundation of China No.52275294.; Oral administration is the most simple, noninvasive, convenient treatment. With the increasing demands on thetargeted drug delivery, the traditional oral treatment now is facing some challenges: 1) biologics how toimp...; 关键词：MICROROBOTS Gastrointestinal tract Oral administration Drug delivery BIOLOGICS

Clinical and laboratory features of juvenile idiopathic arthritis with wrist involvement:Results of a retrospective cohort study: 《World Journal of Clinical Pediatrics》2024年第3期22-33,共12页Lyubov Sorokina Maria Kaneva Artem Artamonov Natalia Gordeeva Irina Chikova Mikhail Kostik; Supported by Ministry of Science and Higher Education of the Russian Federation,No.075-15-2022-301.; BACKGROUND Previous studies in the pre-biological era showed an association of wrist inflammation in juvenile idiopathic arthritis(JIA)with progressive disease course,polyarticular involvement and failure of methotrex...; 关键词：WRIST HAND Juvenile idiopathic arthritis OUTCOMES BIOLOGICS METHOTREXATE

BIOLOGICS