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BACKGROUND Prevalence of the main rheumatic diseases in the Republic of Sakha(Yakutia)[RS(Y)],one of the regions of the Russian Federation,differs from the other regions of the Russian Federation due to its ethnic and...
Background: Non-radiographic axial spondyloarthritis is a progressive and disabling inflammatory disease affecting young adults, with limited treatment options. TNFi are more efficacious than JAKi and IL1-7i in nr-ax ...
Introduction: Spondyloarthritis (SpA) comprises a group of chronic inflammatory rheumatic diseases characterized by predominant axial involvement. These include ankylosing spondylitis (AS), reactive arthritis (ReA), p...
supported by grants to NH from the Canadian Institute of Health Research(CIHR)and Arthritis Society(Canada);AN is a recipient of a CIHR fellowship,Spondyloarthritis Research and Treatment Network(SPARTAN)fellowship,Spondyloarthritis Research Consortium of Canada(SPARCC)fellowship,Edward Christie Stevens fellowship;S.Fenwick Research fellowship,and Krembil Research Institute fellowship(Canada);IJ was supported in part by funding from the Natural Sciences Research Council(NSERC#203475);Canada Foundation for Innovation(CFI#225404,#30865);Ontario Research Fund(RDI#34876,RE010-020);IBM and Ian Lawson van Toch Fund.THK was supported by funding from the National Research Foundation(NRF)of Korea(NRF-2021R1A6A1A03038899);the Korea Healthy Industry Development Institute(HI23C0661).
The hallmarks of spondyloarthritis(SpA)are type 3 immunity-driven inflammation and new bone formation(NBF).Macrophage migration inhibitory factor(MIF)was found to be a key driver of the pathogenesis of SpA by amplifyi...
supported by the Clinical Application-oriented Med-ical Innovation Foundation from National Clinical Research Center for Orthopedics,Sports Medicine&Rehabilitation(Grant No.2021-NCRC-CXJJ-PY-27);Applied Basic Research Project of Logistics Support Department of CMC(Grant No.21BJZ16).
Background Ankylosing spondylitis(AS)generally occurs in young adults.The functional impairments resulting in limitation in activities and social participation might exert lifetime impacts.The present study investigat...
supported by grants from the National Natural Science Foundation of China(Nos.81971532,81971533);the clinical research incubation program of Jiangsu Province Hospital.
To the Editor:Axial spondyloarthritis(axSpA)is a chronic inflammatory disease.[1]The hallmark of ankylosing spondylitis(AS)phenotype is sacroiliac joint and spinal damage characterized by the new bone formation and jo...
To the Editor:Axial spondyloarthritis(axSpA)is characterized by sacroiliac joint inflammation,spine inflammation,bone destruction,and osteogenesis.Ankylosis of the spine and/or hip joints may occur later,significantly...
To the Editor:Axial spondyloarthritis(axSpA)is a chronic and progressive disease affecting the spine and sacroiliac(SI)joints,causing inflammatory back pain,stiffness,and inducing new bone formation(syndesmophytes and...
Background: Concerns exist regarding the risk of infections in patients with spondyloarthritis (SpA) treated with biologics. We assessed the risk of infections of biological and targeted drugs in patients with SpA by ...
To the Editor:Enthesitis is an inflammation of the iliac attachment of ligaments or tendons.In spondyloarthropathies,peripheral enthesitis precedes joint symptoms and is associated with a higher degree of erosive dise...