ARTHRITIS

作品数：487被引量：1155H指数：16
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相关领域：医药卫生更多>>
相关作者：王敏饶平凡范列英叶南慧刘树滔更多>>
相关机构：广州市妇女儿童医疗中心北京大学第二军医大学福州大学更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金北京市自然科学基金更多>>
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Ethnic heterogeneity of juvenile arthritis in the Republic of Sakha(Yakutia)related to a high human leukocyte antigen B27 frequency
《World Journal of Clinical Pediatrics》2025年第2期69-78,共10页Sargylana Boeskorova Marina Afonskaya Vera Argunova Polina Sleptsova Liudmila Leonteva Tatiana Burtseva Mikhail Mikhailovich Kostik 
BACKGROUND Prevalence of the main rheumatic diseases in the Republic of Sakha(Yakutia)[RS(Y)],one of the regions of the Russian Federation,differs from the other regions of the Russian Federation due to its ethnic and...
关键词：Juvenile idiopathic arthritis Human leukocyte antigen B27 Seronegative spondyloarthritis Enthesitis-related arthritis Epidemiology ARTHRITIS YAKUTIA Sakha Human leukocyte antigen B27-associated arthritis Ethnic variation 
Mechanism of AsperosaponinⅥRelated to EGFR/MMP9/AKT/PI3K Pathway in Treatment of Rheumtoid Arthritis
《Chinese Journal of Integrative Medicine》2025年第2期131-141,共11页LUO Jin-fang YU Yang LIU Jian-xin 
Supported by the National Natural Science Foundation of China(Nos.82160779 and 82274178);the 2022 Guizhou Provincial Health Commission Science and Technology Fund Project(No.gzwkj2022-055);Guizhou Science and Technology Plan Project[No.qian ke he ji chu-ZK(2022)Yi ban 477]。
Objective:To explore the mechanism of action of asperosaponinⅥ(AⅥ)in the treatment of rheumatoid arthritis(RA)and validate it in ex vivo experiments using network pharmacology and molecular docking methods.Methods:T...
关键词：inflammation rheumatoid arthritis network pharmacology asperosaponinⅥ EGFR/MMP9/AKT/PI3K pathway 
Protective effect of lappaconitine on Freund's complete adjuvant-induced arthritis exerted through P2X7 receptor-mediated regulation of M1/M2 balance in rats
《Journal of Traditional Chinese Medicine》2025年第1期39-48,共10页ZHANG Pengqiang FENG Qi HUANG Weiyan OU Shan 
OBJECTIVE:to investigate the anti-arthritic effects of lappaconitine(LA)on adjuvant-induced arthritis in Sprague-Dawley rats and its possible involvement in the regulation of M1/M2 macrophage balance through the P2X7 ...
关键词：arthritis experimental macrophage polarization receptors purinergic P2X7 anti-inflammatory agents ANALGESICS LAPPACONITINE 
Chronic intractable nontuberculous mycobacterial-infected wound after acupuncture therapy in the elbow joint:A case report
《World Journal of Clinical Cases》2024年第36期6926-6934,共9页Jong Hyup Kim In Chang Koh Soo Yeon Lim Seong Hee Kang Hoon Kim 
BACKGROUND Musculoskeletal nontuberculous Mycobacterium(NTM)infections are rare,partic-ularly post-acupuncture therapy,and present diagnostic challenges due to their infrequency and potential severity.Prompt recogniti...
关键词：Nontuberculous mycobacteria ARTHRITIS INFECTIOUS Acupuncture Chronic wound Case report 
Arthroscopic patellar denervation with microfracture for treating patellofemoral arthritis in cold weather conditions:a retrospective clinical analysis
《Frigid Zone Medicine》2024年第4期252-256,共5页Xinnan Ma Xin Zhang Yingkai Ma Yonghou Zhao Kai Liu 
supported by grants from the Natural Science Foundation of Heilongjiang Province of China(JQ2020H003);Heilongjiang Postdoctoral Fund(NO.LBH-Z23257);the Innovative Science Research Fund of Harbin Medical University(also known as Heilongjiang Provincial University's Project of Graduate Scientific Research Business Fees)(2022-KYYWF-0274);the Youth TCM scientific research Project of Heilongjiang Province TCM Administration(ZHY2024-283).
Objective:To evaluate the clinical efficacy of combining arthroscopic patellar denervation with microfracture in the treatment of patellofemoral arthritis under cold weather conditions.Methods:A total of 134 patients ...
关键词：arthroscopy patella DENERVATION MICROFRACTURE patellofemoral arthritis cold weather 
Network Meta-analysis of the clinical efficacy and safety of kidney-tonifying and bone-strengthening therapies for the treatment of rheumatoid arthritis with kidney deficiency type
《Journal of Traditional Chinese Medicine》2024年第6期1067-1081,共15页GAN Chang TAO Qingwen YI Haoying BIAN Yuting WANG Jianming 
the National Natural Science Foundation of China:Therapy which Invigorating Kidney and Strengthening Bone Regulates the Balance between Osteoblast and Osteoclast in Treating Rheumatoid Arthritis Bone Destruction:a Mechanism Study (No. 82074223);the Therapeutic Method of Tonifying Kidney and Strengthening Bone Regulates the Bone Marrow Mesenchymal Stem Cells’ Differentiation in Treating Rheumatoid Arthritis:a Mechanism Study (No. 82274435);the Fifth Batch of National Training Program for Clinical Excellence in Chinese Medicine (No. 2022178)。
OBJECTIVE: To compare the efficacy and safety of different Traditional Chinese Medicine(TCM)-based kidney-tonifying and bone-strengthening therapies for rheumatoid arthritis(RA). METHODS: The current Bayesian network ...
关键词：ARTHRITIS RHEUMATOID Medicine Chinese Traditional tonifying kidney and strengthening bones network Metaa-nalysis 
Construction and validation of a risk prediction model for depressive symptoms in a middle-aged and elderly arthritis population
《World Journal of Orthopedics》2024年第12期1164-1174,共11页Jun-Wei Shi Wei Kang Xin-Hao Wang Jin-Long Zheng Wei Xu 
Supported by the Changning District Health Committee Excellent Innovation Talent Training Project,No.RCJD2022S01.
BACKGROUND Arthritis is a prevalent and debilitating condition that affects a significant proportion of middle-aged and older adults worldwide.Characterized by chronic pain,inflammation,and joint dysfunction,arthritis...
关键词：Middle-aged and elderly individuals ARTHRITIS Depression symptoms Current status Influencing factors Risk prediction models 
Bimetallic clusterzymes-loaded dendritic mesoporous silica particle regulate arthritis microenvironment via ROS scavenging and YAP1 stabilization
《Bioactive Materials》2024年第12期613-627,共15页Yang Jin Chuan Hu Jiechao Xia Dingqi Xie Lin Ye Xinyi Ye Li Jiang Honghai Song Yutao Zhu Sicheng Jiang Weiqing Li Weiming Qi Yannan Yang Zhijun Hu 
supported by the Natural Science Foundation of Zhejiang Province of China(No.LY22H060003);The National Natural Science Foundation of China(82470903 to LJ);the Natural Science Foundation of Zhejiang Province(LY24C110001 to LJ).
Clusterzymes are synthetic enzymes exhibiting substantial catalytic activity and selectivity,which are uniquely driven by single-atom constructs.A dramatic increase in antioxidant capacity,158 times more than natural ...
关键词：Clusterzyme Sustained delivery Reactive oxygen species Hippo pathway Rabbit anterior cruciate ligament transection model 
Evaluation indicators of Traditional Chinese Medicine syndromes for gouty arthritis with damp heat accumulation and the effect of administering Tongfeng Qingxiao formula(痛风清消方)
《Journal of Traditional Chinese Medicine》2024年第6期1204-1216,共13页ZHANG Xiaoyun LI Yongjin LI Huanan CHAI Yuan CHENG Feng LI Binglin ZHOU Yi LAI Yu 
the National Natural Science Foundation of China:a Study on the Use of Tongfengqingxiao for Treating Gouty Arthritis and Neutrophil Extracellular Traps Formation based on the Transforming Growth Factor-β1 Signaling Pathway (No. 81860857);a Study on the Mechanism by which Tongfeng Qingxiao Regulates the Toll-like receptors-myeloid Differentiation Factor 88-nuclear Factor Kappa-B Signaling Pathway in Gouty Arthritis Rats with Gut Dysbiosis and Dampness-Heat Syndrome based on the Gut-enteric-microbiota Axis (No. 82060871);National Natural Science Foundation of Jiangxi Province:a Study on the Regulatory Mechanism of the Toll-like receptors-Myeloid differentiation factor 88-nuclear factor kappa-B Signaling Pathway Related to Dysbacteriosis of the Intestinal Flora with Gouty Arthritis in Rats Mediated by Tongfengqingxiao,based on the “Gut-Microbiota” Axis (No. 20202BAB206071)。
OBJECTIVE: To evaluate the indicators of an animal model of gouty arthritis(GA) with dampness heat accumulation and the intervention effect of Tongfeng Qingxiao formula(痛风清消方, TFQXF). METHODS: Seventy-two healthy...
关键词：ARTHRITIS GOUTY uric acid damp heat accumulation Tongfeng Qingxiao formula 
Moxibustion inhibits the macrophage M1 polarization toll-like receptor 4/myeloid differentiation factor 88/nuclear factor kappa B signaling pathway by regulating T-cell immunoglobulin and mucin-containing protein-3 in rheumatoid arthritis
《Journal of Traditional Chinese Medicine》2024年第6期1227-1235,共9页LUO Kun ZHONG Yumei GUO Yanding ZHANG Linlin HU Danhui MA Wenbin YANG Xin ZHOU Haiyan 
the National Natural Science Foundation of China:Study on Immunoregulatory Mechanism of Moxibustion"Regulating Weiqi"to Regulate the Intrasynovial Environment Steady State in Rheumatoid Arthritis Model Rats based on the Skin-resident Memory T cells-Growth Arrest-specific 6/Mer Tyrosine Kinase (No. 82374587);the National Natural Science Foundation of China:Study on the Immune Mechanisms of Macrophage M1/M2 Polarization in the Treatment of Rheumatoid Arthritis by Moxibustion"Strengthening Body Resistance and Eliminating Evil"(No. 81973959);the National Key R&D Program of China:Research on the Functional Characteristics of"Special Effects"and"Common Effects"of Acupoints (No. 2019YFC1709001);Science and Technology Innovation Seedling Project of Sichuan Province:based on Macrophage M1 Polarization Signaling Pathway Toll-like receptor 4/Myeloid differentiation factor 88/Nuclear factor kappa B and its Regulatory Molecule T-cell Immunoglobulin and Mucin-containing Protein-3 Exploring the Effect Mechanism of Moxibustion on Experimental Rheumatoid Arthritis Model (No. 2022037)。
OBJECTIVE: To explore whether moxibustion exerts therapeutic effects on rheumatoid arthritis(RA) by regulating the expression of T-cell immunoglobulin and mucin-containing protein-3(TIM-3) and subsequently modulating ...
关键词：MOXIBUSTION ARTHRITIS RHEUMATOID TIM-3 macrophage polarization toll-like receptor 4 myeloid differentiation factor 88 nuclear factor kappa B signal transduction 
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