the National Natural Science Foundation of China:Therapy which Invigorating Kidney and Strengthening Bone Regulates the Balance between Osteoblast and Osteoclast in Treating Rheumatoid Arthritis Bone Destruction:a Mechanism Study (No. 82074223);the Therapeutic Method of Tonifying Kidney and Strengthening Bone Regulates the Bone Marrow Mesenchymal Stem Cells’ Differentiation in Treating Rheumatoid Arthritis:a Mechanism Study (No. 82274435);the Fifth Batch of National Training Program for Clinical Excellence in Chinese Medicine (No. 2022178)。
OBJECTIVE: To compare the efficacy and safety of different Traditional Chinese Medicine(TCM)-based kidney-tonifying and bone-strengthening therapies for rheumatoid arthritis(RA). METHODS: The current Bayesian network ...
the National Natural Science Foundation of China:Study on Immunoregulatory Mechanism of Moxibustion"Regulating Weiqi"to Regulate the Intrasynovial Environment Steady State in Rheumatoid Arthritis Model Rats based on the Skin-resident Memory T cells-Growth Arrest-specific 6/Mer Tyrosine Kinase (No. 82374587);the National Natural Science Foundation of China:Study on the Immune Mechanisms of Macrophage M1/M2 Polarization in the Treatment of Rheumatoid Arthritis by Moxibustion"Strengthening Body Resistance and Eliminating Evil"(No. 81973959);the National Key R&D Program of China:Research on the Functional Characteristics of"Special Effects"and"Common Effects"of Acupoints (No. 2019YFC1709001);Science and Technology Innovation Seedling Project of Sichuan Province:based on Macrophage M1 Polarization Signaling Pathway Toll-like receptor 4/Myeloid differentiation factor 88/Nuclear factor kappa B and its Regulatory Molecule T-cell Immunoglobulin and Mucin-containing Protein-3 Exploring the Effect Mechanism of Moxibustion on Experimental Rheumatoid Arthritis Model (No. 2022037)。
OBJECTIVE: To explore whether moxibustion exerts therapeutic effects on rheumatoid arthritis(RA) by regulating the expression of T-cell immunoglobulin and mucin-containing protein-3(TIM-3) and subsequently modulating ...
Objective: The aim of this research was to find out if reconstructive surgery is the best option to improve the quality of life of patients with rheumatoid arthritis compared to other monotherapy or combination therap...
the National Science Foundation of China(82130073 and 61973206);Shanghai Leading Talents Program in 2020(110);Science and Technology Commission of Shanghai Municipality(23ZR1437600,23S31905900);Biomaterials and Regenerative Medicine Institute Cooperative Research Project,Shanghai Jiaotong University School of Medicine(2022LHA01);Science and Technology Commission of Shanghai Municipality(23S31905900);Shanghai Pujiang Program(21PJ1409200);China Postdoctoral Science Foundation(2022M722122);Shanghai Frontiers Science Center of Degen-eration and Regeneration in Skeletal System,and the Project of Biobank(YBKB202118)from Shanghai Ninth People's Hospital,Shanghai Jiao Tong University School of Medicine.
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease accompanied by persistent multiarticular synovitis and cartilage degradation. The present clinical treatments are limited to disease-modifying ant...
Grants from the National Natural Science Foundation of China:Study on the Immune Mechanism of Macrophages 1/Macrophages 2 Polarization of Macrophages Treated with Moxibustion"Strengthening the Body and Expelling Pathogenic Qi"for"Struggle Between Healthy Qi and Pathogenic Qi"in Rheumatoid Arthritis(No.81973959);the National Key R&D Program of China:a Comparative Study of Moxibustion at Zusanli(ST36)on the Polarization of Knee Synovial Macrophage in Kneeosteoar-thritis and Rheumatoid Arthritis Rat Models(No.2019YFC1709001);the National Natural Science Foundation of China:Study on the Regulatory Mechanism of the"Immune-Inflammation"Molecular Signal of the Nucleotide—Binding Oligomerization Domain,Leucine rich Repeat and Pyrin domain containing Proteins 3 Inflammasome Treated by Moxibustion for Rheumatoid Arthritis(No.81774435);the Foundation of Chengdu University of Traditional Chinese Medicine:Study on the Mechanism of"Macrophage Migration Inhibitory Factor-Target Protein-Glucocorticoid-Inflammation"in Moxibustion Treatment and Anti-inflammatory Effect of Rheumatoid Arthritis(No.QNXZ2018034);the Science and Technology Innovation Seedling Project of Sichuan Province:Exploring the Effector Mechanism of Moxibustion Treatment in the Experimental Rheumatoid Arthritis Model based on the Macrophage Macrophages 1 Polarization Signaling Pathway Toll-like Receptors 4-Maximum Tolerated Dose 88-Nuclear Factor-Kappa B and its Regulatory Molecule T Cell Immunoglobulin and Mucin Domain-containing Protein 3(No.2022037)。
OBJECTIVE:To determine whether moxibustion had an anti-inflammatory effect on rheumatoid arthritis(RA)by regulating Annexin 1 expression and interfering with the phospholipaseA2 signaling pathway.METHODS:Thirty male S...
Objective To evaluate the efficacy and safety of Wangbi Capsule(WBC)in the treatment of active rheumatoid arthritis(RA).Methods Totally 101 patients in line with inclusion criteria from 114 patients with active RA wer...
Objective:Rheumatoid nephropathy is one of the most severe extra-articular manifestations of rheumatoid arthritis(RA)associated with a very unfavorable prognosis.This study aimed to identify changes in renal function ...
Supported by State Administration of Traditional Chinese Medicine High-level Key Discipline Construction Project of Traditional Chinese Medicine-Ethnic Minority Pharmacy (Zhuang Pharmacy) (zyyzdxk-2023165);Young Talent Cultivation Program of Guangxi International Zhuang Medicine Hospital (2022001);Key R&D Project of Guangxi Science and Technology Department (Guike AB21196057);Guangxi Traditional Chinese Medicine Interdisciplinary Innovation Team Project (GZKJ2309);Funding Project of High-level Talent Cultivation and Innovation Team of Guangxi University of Chinese Medicine (2022A008);The Third Batch of"Qihuang Project"High-Level Talent Team Training Project of Guangxi University of Chinese Medicine (202414);Three-year Action Plan for the Construction of High-level Talents Team of Guangxi International Zhuang Medicine Hospital in 2023 (GZCX20231203).
[Objectives]To investigate the anti-inflammatory effect of Embelia parviflora Wall.polysaccharide on rheumatoid arthritis(RA)in rats.[Methods]RA rat model was induced by type II collagen.After successful modeling,the ...
Researchers have identified a new interaction mode between gut microbiota and immune homeostasis of the synovium in modulating autoimmune responses in rheumatoid arthritis(RA),according to a new study published in Cel...
National Natural Science Foundation of China:a Metabolomic Study of the Effects of Moxibustion on Cardiac Function and Its Intervention in RA Model Rats Based on the TGF-β1/Smads Signaling Pathway (No.81403484);Anhui Province University Natural Science Fund Project of China:Exploring the Mechanism of Action of Moxibustion in AA Rats Based on Intestinal Flora and TLR4/NF-KB Signaling Pathway (No.KJ2019A0448);National Project Cultivation Fund Project Plan:Exploring the Mechanism of Action of Moxibustion in AA Rats Based on Intestinal Flora and TLR4/NF-KB Signaling Pathway (No.2019py01);Anhui Province Clinical Medical Research Center [Anhui Provincial Science and Technology Department Anhui Social Science (2020) No.41];the training Program of Outstanding talents in Colleges and Universities:2021 Domestic Visiting Training Program for Outstanding Young Key Teachers in Colleges and Universities (No.gxgnfx2021122)
OBJECTIVE:To examine the effects of moxibustion on myocardial injury and myocardial metabolomics in rats with rheumatoid arthritis(RA)based on the transforming growth factor beta1(TGF-β1)/Smads signaling pathway.METH...