ANALGESICS

作品数：58被引量：92H指数：5
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相关领域：医药卫生更多>>
相关作者：曹丽敏张锦明何义杰刘中华田嘉禾更多>>
相关机构：华中科技大学新疆分析测试研究院中国药科大学中国人民解放军总医院更多>>
相关期刊：《Acta Pharmacologica Sinica》《Pain Studies and Treatment》《World Journal of Gastroenterology》《BMEMat(BioMedical Engineering Materials)》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金浙江省中医药科技计划项目更多>>
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Effect of electroacupuncture on pain after periodontal flap surgery:a randomized controlled trial
《Journal of Traditional Chinese Medicine》2025年第1期184-191,共8页Emre Bulut Didem Özkal Eminoğlu Yasemin Çayır 
OBJECTIVE:To examine the effect of electroacupuncture(EA)application on postoperative pain levels and the amount of analgesic use in patients who underwent periodontal flap surgery.METHODS:In this prospective,randomiz...
关键词：ELECTROACUPUNCTURE pain postoperative ANALGESICS PERIODONTITIS randomized controlled trial 
Protective effect of lappaconitine on Freund's complete adjuvant-induced arthritis exerted through P2X7 receptor-mediated regulation of M1/M2 balance in rats
《Journal of Traditional Chinese Medicine》2025年第1期39-48,共10页ZHANG Pengqiang FENG Qi HUANG Weiyan OU Shan 
OBJECTIVE:to investigate the anti-arthritic effects of lappaconitine(LA)on adjuvant-induced arthritis in Sprague-Dawley rats and its possible involvement in the regulation of M1/M2 macrophage balance through the P2X7 ...
关键词：arthritis experimental macrophage polarization receptors purinergic P2X7 anti-inflammatory agents ANALGESICS LAPPACONITINE 
Quasi-Static, Poiseuille Flow of Analgesics from an Elastomeric Pump: Theoretical Determination of Infusion Times and Toxicity Conditions
《Journal of Biosciences and Medicines》2024年第9期251-265,共15页Clare B. Lipscombe Trevor C. Lipscombe Don S. Lemons 
Background: Elastomeric pumps (elastic balls into which analgesics or antibiotics can be inserted) push medicines through a catheter to a nerve or blood vessel. Since elastomeric pumps are small and need no power sour...
关键词：Elastomeric Pump Infusion Therapy Bio-Fluids Medical Devices Antibiotic Delivery Analgesic Delivery 
Trends in oxycodone and oxycodone-containing analgesics administration for back pain in emergency departments in the USA(2007–2018)
《World Journal of Emergency Medicine》2024年第3期169-174,共6页Jonathan Chabon Jemer Garrido Deanna Schreiber-Gregory Jefferson Drapkin Sergey Motov 
BACKGROUND:To describe trends in oxycodone and oxycodone-containing analgesic prescribing for the treatment of back pain among adults in emergency departments(EDs) in the USA from 2007 to 2018.METHODS:Data were gather...
关键词：OXYCODONE Back pain Emergency department 
Pain management in chronic pancreatitis
《World Journal of Clinical Cases》2024年第12期2016-2022,共7页Deb Sanjay Nag Bhanu Pratap Swain Rishi Anand Tapas Kumar Barman Vatsala 
Pain in chronic pancreatitis(CP)is difficult to manage.Many patients suffer from inadequate pain relief,completely incapacitating them in their daily activities.Historically,despite their well-known adverse effects,op...
关键词：PANCREATITIS Abdominal pain Palliative care ANALGESICS Life style PSYCHOLOGY 
Analgesic nanomedicines for the treatment of chronic pain
《BMEMat(BioMedical Engineering Materials)》2024年第1期76-87,共12页Hao Liu Hongjun Zhuang Ya Wang Yuen Yee Cheng Feixiang Chen Jian Chen Xinglei Song Run Zhang Yanyan Liu Wenbo Bu 
National Natural Science Youth Fund,Grant/Award Number:82202326;Natural Science Foundation of Shanghai Municipality,Grant/Award Number:21ZR1405300;National Natural Science Foundation of China Youth Fund,Grant/Award Number:52322213;Shanghai Rising-Star Program,Grant/Award Number:21QA1400900;National Funds for General Projects,Grant/Award Number:52272269;Innovation Program of Shanghai Municipal Education Commission,Grant/Award Number:2023ZKZD01;Key Program of National Natural Science Foundation of China,Grant/Award Number:22235004。
Chronic pain is a major cause of suffering that often accompanies diseases and therapies,affecting approximately 20%of individuals at some point in their lives.However,current treatment modalities,such as anesthetic a...
关键词：ANALGESICS chronic pain local anesthetics NANOMEDICINE NEUROPLASTICITY 
Why pharmacovigilance of traditional medicines used as analgesics is important?
《Traditional Medicine Research》2023年第10期47-55,共9页Subhransu Dash Neha Bajwa Abinash Choudhury Preet Amol Singh 
Traditional remedies have gained recognition for their effectiveness in treating various conditions such as diabetes,arthritic pain,liver disease,cough and cold,memory enhancement,and immunological stimulation.Their p...
关键词：herbal medicine PHARMACOVIGILANCE regulatory framework traditional medicine 
Naphthylisoquinoline alkaloids,a new structural template inhibitor of Nav1.7 sodium channel
《Acta Pharmacologica Sinica》2023年第9期1768-1776,共9页Qiao-qiao Wang Long Wang Wen-bo Zhang Chun-ping Tang Xue-qin Chen Yue-ming Zheng Sheng Yao Zhao-bing Gao Yang Ye 
supported by the National Science Fund for Distinguished Young Scholars (grant No.81825021);the Youth Innovation Promotion Association of the Chinese Academy of Sciences (grant No.2020284);the Fund of Science and Technology Commission of Shanghai Municipality (grant No.19431906000);the Key-Area Research and Development Program of Guangdong Province (grant No.2020B0303070002);High-level New R&D Institute (grant No.2019B090904008);High-level Innovative Research Institute (grant No.2021B0909050003)from Department of Science and Technology of Guangdong Province,Zhongshan Municipal Bureau of Science and Technology;the Lingang Laboratory (LG202103-01-06,LG202103-01-05);the National Science and Technology Innovation 2030 Major Program (grant No.2021ZD0200900).
Voltage-gated sodium channel 1.7(Nav1.7)remains one of the most promising drug targets for pain relief.In the current study,we conducted a high-throughput screening of natural products in our in-house compound library...
关键词：Nav1.7 channel naphthylisoquinolines Ancistrocladus tectorius dorsal root ganglion neurons formalin-induced mouse inflammatory painmodel ANALGESICS 
Rhodauricanol A, an analgesic diterpenoid with an unprecedented5/6/5/7 tetracyclic system featuring a unique16-oxa-tetracyclo[11.2.1.0^(1,5).0^(7,13)]hexadecane core from Rhododendron dauricum被引量：1
《Chinese Chemical Letters》2023年第4期183-187,共5页Yuanyuan Feng Suqin Zha Hanqi Zhang Biao Gao Guijuan Zheng Pengfei Jin Yingyi Chen Guangmin Yao 
supported by the Fund of State Key Laboratory of Phytochemistry and Plant Resources in West China (NoP2022-KF08);National Natural Science Foundation of China (Nos.22107033 and U1703109);the Scientific Research Project of Traditional Chinese Medicine of Hubei Provincial Health Commission (No. ZY2021M056)。
A novel diterpenoid with an unprecedented 5/6/5/7 tetracyclic system, rhodauricanol A(1), five new grayanane-derived diterpenoids, dauricanols A-E(2-6), and five known ones(7-11) were isolated from the flowers of Rhod...
关键词：Rhododendron dauricum L.(Ericaceae) Diterpenoids Single-crystal X-ray diffraction Biosynthetic pathways ANALGESICS 
Highly Oxygenated Dimeric Grayanane Diterpenoids as Analgesics:TRPV1 and TRPA1 Dual Antagonists from Rhododendron molle被引量：3
《Chinese Journal of Chemistry》2022年第19期2285-2295,共11页Lang Huang Guijuan Zheng Yuanyuan Feng Pengfei Jin Biao Gao Hanqi Zhang Xiaomin Ma Junfei Zhou Guangmin Yao 
This work was supported by the Fund of State Key Laboratory of Phytochemistry and Plant Resources in West China(P2022-KF08);the Fund of Laboratory of Xinjiang Native Medicinal and Edible Plant Resource Chemistry(KSUZDSYS202101);the National Natural Science Foundation of China(22107033 and U1703109);the Traditional Chinese Medicine of Hubei Provincial Health Commission(ZY2021M056);the China Postdoctoral Science Foundation(2021M691152)。
Six highly oxygenated dimeric grayanane diterpenoids(1—6)including three new ones,bismollethers A—C(1—3),were isolated from the flowers of Rhododendron molle collected at Qichun,Hubei,China.The structures and relat...
关键词：Biological activity Dimeric grayanane diterpenoids Natural products Rhododendron molle(Ericaceae) Structure elucidation 
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